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首页> 外文期刊>Journal of Experimental Neuroscience >Blurring the Boundaries of Vision: Novel Functions of Intrinsically Photosensitive Retinal Ganglion Cells:
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Blurring the Boundaries of Vision: Novel Functions of Intrinsically Photosensitive Retinal Ganglion Cells:

机译：模糊的视界：本征光敏性视网膜神经节细胞的新功能：

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Mammalian vision consists of the classic image-forming pathway involving rod and cone photoreceptors interacting through a neural network within the retina before sending signals to the brain, and a non image-forming pathway that uses a photosensitive cell employing an alternative and evolutionary ancient phototransduction system and a direct connection to various centers in the brain. Intrinsically photosensitive retinal ganglion cells (ipRGCs) contain the photopigment melanopsin, which is independently capable of photon detection while also receiving synaptic input from rod and cone photoreceptors via bipolar cells. These cells are the retinal sentry for subconscious visual processing that controls circadian photoentrainment and the pupillary light reflex. Classified as irradiance detectors, recent investigations have led to expanding roles for this specific cell type and its own neural pathways, some of which are blurring the boundaries between image-forming and non image-forming visual processes.
机译：哺乳动物的视觉由经典的图像形成途径组成，该过程涉及杆和锥体感光器在向大脑发送信号之前通过视网膜内的神经网络进行交互，以及一种非图像形成途径，该途径使用采用替代性和进化的古老光转导系统的光敏细胞并直接连接到大脑的各个中心。本质上，光敏性视网膜神经节细胞（ipRGC）包含光色素黑素，它既能够独立进行光子检测，又能通过双极细胞接收来自杆和锥光感受器的突触输入。这些细胞是用于控制生物钟光夹带和瞳孔光反射的潜意识视觉处理的视网膜哨兵。分类为辐照度检测器，最近的研究导致这种特定细胞类型及其自身神经通路的作用不断扩展，其中一些正在模糊成像和非成像视觉过程之间的界限。

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