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首页> 外文期刊>Journal of Hainan Medical University >Detection and significance of reproductive hormones, prethrombotic state markers and coagulation related factors in threatened abortion in early pregnancy
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Detection and significance of reproductive hormones, prethrombotic state markers and coagulation related factors in threatened abortion in early pregnancy

机译：妊娠早期先兆流产中生殖激素，血栓前状态标志物和凝血相关因子的检测及其意义

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Objective: To investigate the changes and significance of reproductive hormones, prethrombotic state markers and coagulation related factors in threatened abortion in early pregnancy. Methods: Review the clinical data of threatened abortion in early pregnancy (include continuing pregnancy and miscarriages) and healthy pregnant women in the early pregnancy in our hospital, and the levels of reproductive hormones, prethrombotic state markers and coagulation related factors were compared between the three groups. Results: The results of single factor variance showed that the levels of β-HCG, progesterone, E2, PC, PLG, D-D, TAT, F1+2 and PAI-1 level were all statistically significant. Compared with the control group, the average levels of β-HCG, progesterone, E2 and PLG in the pregnancy maintenance group and the interrupted pregnancy group were significantly decreased, and the level of the interrupted pregnancy group was significantly lower than that of the pregnancy maintenance group. The levels of PC, D-D, TAT, F1+2 and PAI-1 in the pregnancy maintenance group and the interrupted pregnancy group were significantly higher than those in the control group, and the level of the interrupted pregnancy group was significantly higher than that of the pregnancy maintenance group. There was no significant difference in the level of AT III between the groups. Conclusion: There are significant abnormal levels of reproductive hormones, prethrombotic state markers and coagulation related factors in patients with threatened abortion in early pregnancy, the detection of its index level is of great value in predicting threatened abortion in the early stage.
机译：目的：探讨妊娠早期先兆流产中生殖激素，血栓前状态标志物和凝血相关因子的变化及其意义。方法：回顾我院早孕先兆流产（包括持续妊娠和流产）和健康孕妇的临床资料，比较三者的生殖激素，血栓前状态标志物和凝血相关因素组。结果：单因素方差的结果表明，β-HCG，孕酮，E2，PC，PLG，D-D，TAT，F1 + 2和PAI-1含量均具有统计学意义。与对照组相比，妊娠维持组和妊娠中断组的β-HCG，孕激素，E2和PLG的平均水平明显降低，而妊娠中断组的水平明显低于维持妊娠的水平。组。维持妊娠组和中断妊娠组的PC，DD，TAT，F1 + 2和PAI-1水平明显高于对照组，而中断妊娠组的PC，DD，TAT，F1 + 2和PAI-1水平明显高于对照组。维持妊娠组。两组之间的AT III水平没有显着差异。结论：妊娠早期先兆流产患者的生殖激素，血栓前状态标志物和凝血相关因子异常水平显着，其指标水平的检测对早期先兆流产具有重要的预测价值。

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