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首页> 外文期刊>Digest Journal of Nanomaterials and Biostructures >THE FABRICATION OF POROUS HYDROXYAPATITE SCAFFOLD USINGGAUR GUM AS A NATURAL BINDER
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THE FABRICATION OF POROUS HYDROXYAPATITE SCAFFOLD USINGGAUR GUM AS A NATURAL BINDER

机译：天然胶粘剂高尔胶制备多孔羟基磷灰石脚手架的研究

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摘要

In bone tissue engineering, Hydroxyapatite (HA) is extensively used in medicalapplications as an implant material to enhance bone growth formation or as drug releasevehicle because of its resemblance to the components of human bones and for its excellentbiocompatibility. The porous structure is generally used as a scaffolding material. Manytechniqueshave been applied to fabricate HA porous scaffolds. In this work, polymericsponge technique was employed in the preparation of HA scaffold, using gum Ghatti, anatural binder obtained from the barks of Anogeissuslatifolia species. The influence ofbinder concentration for various sintering temperature 1100 oC,1150 oC and 1200 oC wasestimated. The Hydroxyapatite starting powder and Hydroxyapatite scaffold werecharacterized for phase purity, structural analysis, porosity measurements and mechanicalproperties. It is possible to produce Hydroxyapatite scaffolds with highly inter connectingmacro ranging from 500 to 1000 μm and micro pores from 400 to 2000 nm with acompressive strength ranging from 0.43 MPa to 2.62 MPa, comparable to trabacular bone.
机译：在骨组织工程中，羟基磷灰石（HA）由于其与人体骨骼的相似性以及出色的生物相容性，在医疗应用中被广泛用作植入材料以增强骨骼的生长形成或用作药物释放载体。多孔结构通常用作脚手架材料。许多技术已被用于制造HA多孔支架。在这项工作中，聚合物胶技术用于HA支架的制备中，使用的是Ghatti胶，一种从Anogeissuslatifolia种类的树皮中获得的天然粘合剂。估算了粘结剂浓度对1100 oC，1150 oC和1200 oC各种烧结温度的影响。表征了羟基磷灰石原料粉末和羟基磷灰石支架材料的相纯度，结构分析，孔隙率测量和力学性能。可以生产具有高度相互连接的宏观范围为500至1000μm，微孔为400至2000 nm且抗压强度范围为0.43 MPa至2.62 MPa的羟基磷灰石支架，与小梁骨相当。

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