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首页> 外文期刊>Digest Journal of Nanomaterials and Biostructures >INVESTIGATION ON OPTICAL, DIELECTRIC AND INVITROANTI-INFLAMMATORY RESPONSES OF TITANIUM DIOXIDE (TiO2)NANOPARTICLES
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INVESTIGATION ON OPTICAL, DIELECTRIC AND INVITROANTI-INFLAMMATORY RESPONSES OF TITANIUM DIOXIDE (TiO2)NANOPARTICLES

机译：二氧化钛（TiO2）纳米微粒的光学，介电和离体炎症反应研究

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摘要

This article deals with synthesis of titanium dioxide (TiO2) nanoparticles using sol-gelmethod. The morphological as well as optical and dielectric properties were determined.The anti-inflammatory properties of the synthesized nanoparticles were observed throughin vitro assessment. For specified concentration of TiO2 nanoparticles under restrictedexperimental conditions, the absorbance was measured to evaluate the anti-inflammatoryproperty. The morphological features and particle size with their crystal structure weredetermined by scanning electron microscopy (SEM), transmission electron microscopy(TEM) and powder X-ray diffraction (XRD). The optical properties of TiO2 nanoparticleswere measured using UV-vis. absorption spectroscopy and photoluminescence (PL)spectroscopy. The FT-IR and Raman spectra analyses were also conducted that confirmedthe presence of TiO2nanoparticles. Under predetermined frequency and temperature level,the dielectric properties including dielectric constant, dielectric loss and AC conductivityof the synthesized TiO2nanoparticles were determined. The findings indicated the antiinflammatoryproperties of TiO2 through in vitro assessment. The research also exhibitedthe inhibition of protein denaturation, protease inhibition and hemolytic assay for thesynthesized Nano particles of TiO2.
机译：本文涉及使用溶胶-凝胶法合成二氧化钛（TiO2）纳米粒子。确定了形态，光学和介电性能。通过体外评估观察了合成纳米颗粒的抗炎性能。对于在限制的实验条件下指定浓度的TiO2纳米颗粒，测量吸光度以评估抗炎性能。通过扫描电子显微镜（SEM），透射电子显微镜（TEM）和粉末X射线衍射（XRD）确定其形态特征和粒径及其晶体结构。 TiO 2纳米颗粒的光学性质是使用紫外可见光谱仪测量的。吸收光谱和光致发光（PL）光谱。还进行了FT-IR和拉曼光谱分析，证实了TiO2纳米粒子的存在。在预定的频率和温度水平下，测定了合成的TiO2纳米粒子的介电性能，包括介电常数，介电损耗和交流电导率。这些发现通过体外评估表明了TiO2的抗炎特性。该研究还显示了对合成的TiO2纳米颗粒的蛋白质变性抑制，蛋白酶抑制和溶血分析。

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