...
  • 主题
高级搜索  >
历史搜索 清空历史
首页> 外文期刊>Journal of Hainan Medical University >Effects of symbicort turbuhaler combined with tiotropium bromide on serum PCT, TIMP-1, MMP-9, IFN-γ, arterial blood gases and pulmonary function in patients with AECOPD
【24h】

Effects of symbicort turbuhaler combined with tiotropium bromide on serum PCT, TIMP-1, MMP-9, IFN-γ, arterial blood gases and pulmonary function in patients with AECOPD

机译：复方沙丁草胺联合噻托溴铵对AECOPD患者血清PCT，TIMP-1，MMP-9，IFN-γ，动脉血气和肺功能的影响

获取原文
           
页面导航
  • 摘要
  • 著录项
  • 相似文献
  • 相关主题

摘要

Objective: To study the effects of symbicort turbuhaler combined with tiotropium bromideon serum PCT, TIMP-1, MMP-9, IFN-γ, arterial blood gases and pulmonary function inpatients with AECOPD. Methods A total of 90 patients in our hospital with AECOPD duringJanuary 2014 to January 2017 were divided into the control group (n=45) and the treatmentgroup (n=45) randomly. The control group was treated with tiotropium bromide; the treatmentgroup was treated with symbicort turbuhaler combined with tiotropium bromide. The twogroups were treated for 14 d. That was compared of the serum PCT, TIMP-1, MMP-9, IFN-γ,PaO2, SaO2, PaCO2, MPAP, PASP and PADP of the two groups before and after treatment.Results The serum PCT, TIMP-1, MMP-9, IFN-γ, PaO2, SaO2, PaCO2, MPAP, PASP andPADP of the two groups before treatment have no significantly differences. The serum PCT,TIMP-1, MMP-9 and IFN-γ levels of the two groups after treatment were significantly lowerthan before treatment. The serum PCT, TIMP-1, MMP-9 and IFN-γ levels of the treatmentgroup after treatment were significantly lower than the control group. The PaO2, SaO2 ofthe two groups after treatment were significantly higher than before treatment, the PaCO2,MPAP, PASP and PADP of the two groups after treatment were significantly lower than beforetreatment. The PaO2, SaO2, PaCO2, MPAP, PASP and PADP of the treatment group aftertreatment were significantly better than the control group. Conclusion Symbicort turbuhalercombined with tiotropium bromide can reduce the serum PCT, TIMP-1, MMP-9, IFN-γlevels and the pulmonary arterial hypertension, improve the lung tissue oxygen supply and thecardiopulmonary function, and it was worthy clinical application.
机译：目的：研究复方沙丁胺醇联合噻托溴铵溴化eon血清对AECOPD患者PCT，TIMP-1，MMP-9，IFN-γ，动脉血气和肺功能的影响。方法将2014年1月至2017年1月我院收治的AECOPD患者90例随机分为对照组（n = 45）和治疗组（n = 45）。对照组给予噻托溴铵治疗;治疗组采用西必克尔turbuhaler联合噻托溴铵治疗。两组均治疗14 d。比较两组患者治疗前后血清PCT，TIMP-1，MMP-9，IFN-γ，PaO2，SaO2，PaCO2，MPAP，PASP和PADP的含量。结果血清PCT，TIMP-1，MMP -9，治疗前两组的IFN-γ，PaO2，SaO2，PaCO2，MPAP，PASP和PADP无明显差异。两组治疗后血清PCT，TIMP-1，MMP-9和IFN-γ水平明显低于治疗前。治疗后治疗组的血清PCT，TIMP-1，MMP-9和IFN-γ水平明显低于对照组。两组治疗后的PaO2，SaO2均明显高于治疗前，两组的PaCO2，MPAP，PASP和PADP均明显低于治疗前。治疗组治疗后的PaO2，SaO2，PaCO2，MPAP，PASP和PADP明显优于对照组。结论Symbicort turbuhaler联合噻托溴铵可降低血清PCT，TIMP-1，MMP-9，IFN-γ水平和肺动脉高压，改善肺组织供氧和心肺功能，值得临床应用。

著录项

相似文献

  • 外文文献
  • 中文文献
  • 专利
获取原文

客服邮箱：kefu@zhangqiaokeyan.com

京公网安备：11010802029741号 ICP备案号：京ICP备15016152号-6 六维联合信息科技 (北京) 有限公司©版权所有

  • 客服微信

  • 服务号