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The Japanese Clinical Practice Guidelines for Management of Sepsis and Septic Shock 2016 (J-SSCG 2016)

机译:《日本脓毒症和脓毒性休克管理临床实践指南2016》(J-SSCG 2016)

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Background and purpose The Japanese Clinical Practice Guidelines for Management of Sepsis and Septic Shock 2016 (J-SSCG 2016), a Japanese-specific set of clinical practice guidelines for sepsis and septic shock created jointly by the Japanese Society of Intensive Care Medicine and the Japanese Association for Acute Medicine, was first released in February 2017 and published in the Journal of JSICM , [2017; Volume 24 (supplement 2)] https://doi.org/10.3918/jsicm.24S0001 and Journal of Japanese Association for Acute Medicine [2017; Volume 28, (supplement 1)] http://onlinelibrary.wiley.com/doi/10.1002/jja2.2017.28.issue-S1/issuetoc . This abridged English edition of the J-SSCG 2016 was produced with permission from the Japanese Association of Acute Medicine and the Japanese Society for Intensive Care Medicine. Methods Members of the Japanese Society of Intensive Care Medicine and the Japanese Association for Acute Medicine were selected and organized into 19 committee members and 52 working group members. The guidelines were prepared in accordance with the Medical Information Network Distribution Service (Minds) creation procedures. The Academic Guidelines Promotion Team was organized to oversee and provide academic support to the respective activities allocated to each Guideline Creation Team. To improve quality assurance and workflow transparency, a mutual peer review system was established, and discussions within each team were open to the public. Public comments were collected once after the initial formulation of a clinical question (CQ) and twice during the review of the final draft. Recommendations were determined to have been adopted after obtaining support from a two-thirds (>?66.6%) majority vote of each of the 19 committee members. Results A total of 87 CQs were selected among 19 clinical areas, including pediatric topics and several other important areas not covered in the first edition of the Japanese guidelines (J-SSCG 2012). The approval rate obtained through committee voting, in addition to ratings of the strengths of the recommendation, and its supporting evidence were also added to each recommendation statement. We conducted meta-analyses for 29 CQs. Thirty-seven CQs contained recommendations in the form of an expert consensus due to insufficient evidence. No recommendations were provided for five CQs. Conclusions Based on the evidence gathered, we were able to formulate Japanese-specific clinical practice guidelines that are tailored to the Japanese context in a highly transparent manner. These guidelines can easily be used not only by specialists, but also by non-specialists, general clinicians, nurses, pharmacists, clinical engineers, and other healthcare professionals.
机译:背景与目的《日本脓毒症和脓毒性休克管理临床实践指南2016》(J-SSCG 2016)是由日本重症监护医学会和日本人共同制定的一套针对日本的脓毒症和脓毒性休克临床实践指南急性医学协会于2017年2月首次发布,并发表在《 JSICM杂志》上,[2017年;第24卷(补编2)] https://doi.org/10.3918/jsicm.24S0001和日本急性医学会杂志[2017;第28卷,(补充1)] http://onlinelibrary.wiley.com/doi/10.1002/jja2.2017.28.issue-S1/issuetoc。本J-SSCG 2016的英文缩写版是在获得日本急性医学会和日本重症监护医学会许可的情况下制作的。方法选择日本重症监护医学会和日本急性医学会成员,将其分为19个委员会成员和52个工作组成员。该指南是根据医学信息网络分发服务(Minds)创建程序而编写的。组织了学术指导促进小组,以监督分配给每个指导创建小组的各项活动并为其提供学术支持。为了提高质量保证和工作流程的透明度,建立了相互的同行评审系统,并且每个团队内部的讨论向公众开放。在最初提出临床问题(CQ)之后,收集公众意见一次,在对最终草案进行审核期间,收集公众意见两次。在获得19位委员会成员中每位成员三分之二(> 66.6%)多数票的支持后,确定已采纳建议。结果在19个临床领域中共选择了87个CQ,包括儿科主题和日本指南第一版(J-SSCG 2012)未涵盖的其他几个重要领域。通过委员会投票获得的批准率,以及对推荐强度的等级评定及其支持证据,也被添加到每个推荐声明中。我们对29个CQ进行了荟萃分析。由于证据不足,共有37个CQ以专家共识的形式提出了建议。没有为五个CQ提供建议。结论基于所收集的证据,我们能够以高度透明的方式制定针对日本情况的针对日本的临床实践指南。这些指南不仅可以由专家轻松使用,而且可以由非专家,普通临床医生,护士,药剂师,临床工程师和其他医疗保健专业人员轻松使用。

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