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首页> 外文期刊>Journal of International Medical Research >The Impact of Clinical Risk Factors in the Conversion from Acute Lung Injury to Acute Respiratory Distress Syndrome in Severe Multiple Trauma Patients
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The Impact of Clinical Risk Factors in the Conversion from Acute Lung Injury to Acute Respiratory Distress Syndrome in Severe Multiple Trauma Patients

机译:重症多发性创伤患者从急性肺损伤向急性呼吸窘迫综合征转化的临床危险因素的影响

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Acute lung injury (ALI) and acute respiratory distress syndrome (ARDS) are different stages of the same disease, the aggravated stage of ALI leading to ARDS. Patients with ARDS have higher hospital mortality rates and reduced long-term pulmonary function and quality of life. It is, therefore, important to prevent ALI converting to ARDS. This study evaluated 17 risk factors potentially associated with the conversion from ALI to ARDS in severe multiple trauma. The results indicate that the impact of pulmonary contusion, APACHE II score, gastrointestinal haemorrhage and disseminated intravascular coagulation may help to predict conversion from ALI to ARDS in the early phase after multiple-trauma injury. Trauma duration, in particular, strongly impacted the short- and long-term development of ALI. Being elderly (aged ≥ 65 years) and undergoing multiple blood transfusions in the early phase were independent risk factors correlated with secondary sepsis, deterioration of pulmonary function and transfusion-related acute lung injury due to early multiple fluid resuscitation.
机译:急性肺损伤(ALI)和急性呼吸窘迫综合征(ARDS)是同一疾病的不同阶段,ALI的加重阶段会导致ARDS。 ARDS患者的住院死亡率更高,长期肺功能和生活质量下降。因此,重要的是防止ALI转换为ARDS。这项研究评估了严重多发性创伤中从ALI转换为ARDS的17个潜在危险因素。结果表明,肺挫伤,APACHE II评分,胃肠道出血和弥散性血管内凝血的影响可能有助于预测多发伤后早期由ALI转变为ARDS。特别是创伤的持续时间,严重影响了ALI的短期和长期发展。老年人(≥65岁)并在早期进行多次输血是与早期败血症,肺功能恶化以及早期进行多次液体复苏导致的输血相关的急性肺损伤相关的独立危险因素。

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