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首页> 外文期刊>Journal of International Medical Research >Age Interactions in Breast Cancer: An Analysis of a 10-Year Multicentre Study in China
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Age Interactions in Breast Cancer: An Analysis of a 10-Year Multicentre Study in China

机译：乳腺癌的年龄相互作用：对中国一项为期十年的多中心研究的分析

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OBJECTIVES: The effects of age at diagnosis on the clinical characteristics of breast cancer and trends over time were investigated in Chinese women. METHODS: Data from 4211 women with pathologically confirmed primary breast cancer collected between 1999 and 2008 for a multicentre retrospective study were analysed according to age at diagnosis. RESULTS: Age at diagnosis ranged from 21 to 86 years, with a mean of 48.7 years, and was shown to be significantly related to tumour size, lymph node status, hormone receptor status and human growth factor receptor-2 status, but not to pathological type or tumour, node, metastasis stage. The age-corrected proportion of patients aged 50 鈥?64 years at diagnosis increased significantly between 1999 and 2008. There was a significant difference in the age-corrected distribution of age at diagnosis in China compared with Western countries. CONCLUSIONS: Age at diagnosis is related to the clinical and pathological characteristics of breast cancer. The age at diagnosis in China increased over the decade from 1999 to 2008, but is still lower than in Western countries.
机译：目的：研究了中国女性在诊断时的年龄对乳腺癌临床特征及其随时间变化趋势的影响。方法：根据诊断时的年龄，对1999年至2008年间经多中心回顾性研究收集的4211名经病理证实的原发性乳腺癌妇女的数据进行了分析。结果：诊断时年龄为21至86岁，平均48.7岁，与肿瘤大小，淋巴结状态，激素受体状态和人类生长因子受体2状态显着相关，但与病理无关类型或肿瘤，淋巴结，转移阶段。在1999年至2008年之间，年龄在50到64岁的被诊断患者的年龄校正比例显着增加。与西方国家相比，中国在诊断时的年龄校正的年龄分布存在显着差异。结论：诊断年龄与乳腺癌的临床和病理特征有关。从1999年到2008年的十年间，中国的确诊年龄有所增加，但仍低于西方国家。

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