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首页> 外文期刊>Journal of Lasers in Medical Sciences >The effect of low level laser therapy on Pemphigus vulgaris lesions: A Pilot Study
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The effect of low level laser therapy on Pemphigus vulgaris lesions: A Pilot Study

机译：低水平激光疗法对寻常性天疱疮病变的影响：一项初步研究

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Background: Pemphigus vulgaris is a chronic blistering skin disease. Management of recalcitrant pemphigus ulcers is a great problem. Low Level Laser Therapy (LLLT) is known to supply direct biostimulative light energy to body cells. Objective: This study evaluates the efficacy of low power laser in the healing of pemphigus lesions. Methods: Ten patients with pemphigus vulgaris were enrolled in the trial. The LED-LLLT system used was the Thor LED clusters (109, 69 or 19 diode) (ENGLAND) with 660 nm wave length in continuous wave (CW) and 30 MW energy. Both sides of the patients’ lesion were photographed prior to the study and in each laser therapy sessions. Results: The pattern of changes in QWS patterns differed significantly over time between the two therapies (treatment × time interactions, p&.0001). When compared to the routine therapy, the laser therapy showed more decreases in mean QWS in all sessions in comparison with baseline. Limitations: This is a pilot study. Conclusion: Application of Low Level Laser simultaneously with conventional therapy could result in sensational healing of ulcers especially in patients who do not respond to conventional treatment or suffering from recalcitrant lesions.
机译：背景：天疱疮是一种慢性水疱性皮肤病。顽固性天疱疮溃疡的管理是一个很大的问题。众所周知，低水平激光疗法（LLLT）可为人体细胞提供直接的生物刺激光能。目的：本研究评估低功率激光在天疱疮皮损愈合中的疗效。方法：本研究共纳入10例寻常型天疱疮患者。使用的LED-LLLT系统是Thor的LED集群（109、69或19二极管）（英国），其连续波（CW）波长为660 nm，能量为30 MW。在研究之前和每次激光治疗中，都要对患者病变的两侧进行拍照。结果：在两种疗法之间，QWS模式的变化模式随时间显着不同（治疗×时间相互作用，p ＜.0001）。与常规疗法相比，激光疗法在所有疗程中的平均QWS均较基线降低更多。局限性：这是一项试点研究。结论：低水平激光与常规治疗同时使用可导致溃疡的感觉愈合，特别是对常规治疗无反应或顽固性病变的患者。

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