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首页> 外文期刊>Journal of Lasers in Medical Sciences >Fractionated CO2 Laser in the Treatment of Striae Alba in Darker Skinned Patients - A Prospective Study
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Fractionated CO2 Laser in the Treatment of Striae Alba in Darker Skinned Patients - A Prospective Study

机译：分次CO2激光治疗深色皮肤患者纹状体的前瞻性研究

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Introduction : In recent years, the positive effect of fractional CO2 laser on increasing collagen fibers, and consequently its effect on treating striae has been suggested. The present study aims to assess the effectiveness of CO2 fractional laser 10600-nm in the treatment of striae alba. Methods : In this prospective clinical trial, 2 treatment sessions of fractional CO2 laser with 4-week interval was given to 30 patients with striae alba. Cutaneous resonance running time (CRRT) was measured at baseline and at week 4 and 3 months after the last session of laser therapy. The level of improvement was assessed by 2 independent dermatologists and patients after 3 months of follow up. Results : 16.7% of patients had moderate improvement, 63.3% had minimal improvement, and 20% had no improvement. A statistical significant difference was found in median CRRT during the study (P & 0.0001). The median CRRT levels were significantly higher in week 4 and 3 months after the last treatment compared to the baseline (both P & 0.001). Likewise, a significant increase was observed in median CRRT level from week 4 till the end of study (P & 0.001). Evaluation of participant satisfaction revealed that 10% were very satisfied, 10% satisfied, 3.3% slightly satisfied, and 76.7% unsatisfied. Conclusion : Striae alba remain a challenging condition to treat. The treatment of striae alba with CO2 fractional laser results in minimal improvement with mild side effects.
机译：简介：近年来，有人提出了分数式CO2激光对增加胶原纤维的积极作用，并因此提出了对纹状体治疗的作用。本研究旨在评估10600 nm CO2分数激光治疗纹状体的有效性。方法：在这项前瞻性临床试验中，对30例纹状体患者进行了2次CO2分段激光治疗，间隔4周。在基线以及激光治疗最后一次疗程后的第4周和第3个月测量皮肤共振运行时间（CRRT）。随访3个月后，由2位独立的皮肤科医生和患者评估了改善水平。结果：16.7％的患者有中度改善，63.3％的患者有轻微改善，20％的患者没有改善。在研究期间中位数CRRT中发现统计学上的显着差异（P ＜0.0001）。与基线相比，最后一次治疗后第4周和第3个月的CRRT中位数显着更高（均P ＜0.001）。同样，从第4周到研究结束，观察到CRRT中值水平显着增加（P ＜0.001）。参与者满意度的评估显示，非常满意的有10％，满意的占10％，稍满意的占3.3％，不满意的占76.7％。结论：白纹病仍然是一个具有挑战性的疾病。用CO2分数激光治疗纹状体白纹效果不明显，且副作用轻微。

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