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首页> 外文期刊>Journal of Lasers in Medical Sciences >Evaluation of the Effects of Low Level Laser Therapy on the Healing Process After Skin Graft Surgery in Burned Patients (A Randomized Clinical Trial)
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Evaluation of the Effects of Low Level Laser Therapy on the Healing Process After Skin Graft Surgery in Burned Patients (A Randomized Clinical Trial)

机译:低水平激光疗法对烧伤患者皮肤移植术后愈合过程的影响评估(一项随机临床试验)

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Background: Skin graft is standard therapeutic technique in patients with deep ulcers but as every surgical procedure has complications. Although several modern dressings are available to enhance comfort of donor site, using techniques that accelerate wound healing may enhance patienta??s satisfaction. Low Level Laser Therapy (LLLT) has been used in several medical fields, especially for wound healing but for treating large ulcers, it may last several months to heal completely. Materials and Methods: The protocols and informed consent were reviewed according to Medical Ethics Board of Shahid Beheshti University of Medical Sciences (IR.SBMU.REC.1394.363) and Iranian Registry of Clinical Trials (IRCT2016020226069N2). Nine patients with bilateral similar grade 3 burn ulcer in both hands or both feet, candidate for Split Thickness Skin Graft (STSG) were selected. One side was selected for laser irradiation and the other side as control, randomly. Laser area was irradiated by red, 655 nm laser light, 150 mW, 2 J/Cm 2 for the bed of the ulcer and infra red 808 nm laser light, 200 mW for the margins, every day for 7 days. Results: The rate of wound dehiscence after skin graft surgery was significantly lower in laser treated group in comparison to control group which received only classic dressing (P=0.019). Discussion: In the present study for the first time we evaluate the effects of LLLT on the healing process of skin grafted area in burn patients. The results showed LLLT is a safe effective method which improves graft survival and wound healing process and decreases the rate of wound dehiscence in patients with deep burn ulcer .
机译:背景:植皮术是深溃疡患者的标准治疗技术,但由于每项外科手术都有并发症。尽管可以使用几种现代敷料来提高供体部位的舒适度,但使用加速伤口愈合的技术可以提高患者的满意度。低水平激光疗法(LLLT)已在多个医学领域中使用,尤其是用于伤口愈合,但对于治疗大溃疡,可能要持续几个月才能完全治愈。材料和方法:根据Shahid Beheshti医学大学医学伦理委员会(IR.SBMU.REC.1394.363)和伊朗临床试验注册中心(IRCT2016020226069N2)对方案和知情同意书进行了审查。选择了9例双侧或双足双侧相似的3级烧伤溃疡的患者,这些患者均选择了“厚皮移植”(STSG)。随机选择一侧进行激光照射,另一侧作为对照。每天用7天的655纳米红色激光,150 mW,2 J / Cm 2的溃疡床和808纳米边缘的红外808 nm激光辐照激光区域。结果:与仅接受经典敷料的对照组相比,激光治疗组的皮肤移植手术后伤口开裂率显着降低(P = 0.019)。讨论:在本研究中,我们首次评估LLLT对烧伤患者皮肤移植区域愈合过程的影响。结果表明,LLLT是一种安全有效的方法,可提高深度烧伤溃疡患者的移植物存活率和伤口愈合过程,降低伤口裂开率。

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