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首页> 外文期刊>Journal of International Medical Research >The association of uric acid with leukoaraiosis
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The association of uric acid with leukoaraiosis

机译:尿酸与白癜风的关系

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Objective To explore the possible correlation between uric acid levels and leukoaraiosis (LA). Methods This cross-sectional study enrolled patients who presented with some neurological discomfort (e.g. dizziness, headache, mild?cognitive?impairment). Potential demographic and clinical risk factors associated with LA, including sex, age, hypertension, diabetes mellitus, smoking, alcohol consumption, dyslipidaemia, plasma fibrinogen, D-dimer, uric acid, and homocysteine, were investigated using univariate and multivariate logistic regression analyses. Results A total of 268 patients were enrolled in the study and divided into the LA group ( n ?=?164) and the non-LA group ( n ?=?104). Compared with the non-LA group, uric acid was significantly higher in the LA group (mean?±?SD: 356.49?±?121.85?μmol/l versus 289.96?±?102.98?μmol/l). Multivariate logistic regression analyses showed that uric acid was an independent risk factor for LA (odds ratio 1.285; 95% confidence interval 1.062, 1.556). Conclusion Hyperuricaemia was an independent risk factor for leukoaraiosis in Chinese patients.
机译:目的探讨尿酸水平与白癜风(LA)的可能关系。方法这项横断面研究招募了表现出某些神经系统不适(例如头晕,头痛,轻度认知障碍)的患者。使用单因素和多元logistic回归分析研究了与LA相关的潜在人口统计学和临床​​风险因素,包括性别,年龄,高血压,糖尿病,吸烟,饮酒,血脂异常,血浆纤维蛋白原,D-二聚体,尿酸和高半胱氨酸。结果共纳入268例患者,分为LA组(n = 164)和非LA组(n = 104)。与非LA组相比,LA组的尿酸明显增高(平均值±±标准差:356.49±±121.85μmol/ l,而289.96±±102.98μmol/ l)。多元逻辑回归分析表明,尿酸是洛杉矶的独立危险因素(赔率为1.285; 95%置信区间为1.062、1.556)。结论高尿酸血症是中国患者白癜风的独立危险因素。

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