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首页> 外文期刊>Journal of International Medical Research >Association between Toxoplasma gondii infection and history of blood transfusion: a case-control seroprevalence study
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Association between Toxoplasma gondii infection and history of blood transfusion: a case-control seroprevalence study

机译：斜体弓形虫感染与输血史之间的关联：一项病例对照的血清阳性率研究

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Objectives This study was performed to determine the association between seropositivity to Toxoplasma gondii and a history of blood transfusion. Methods Patients who had undergone blood transfusion (n?=?410) and age- and sex-matched controls who had not undergone blood transfusion (n?=?1230) were examined for anti- T. gondii IgG and IgM antibodies using enzyme-linked immunoassays. Results Anti- T. gondii IgG antibodies were detected in 57 (13.9%) patients and in 129 (10.5%) controls with a borderline difference [odds ratio (OR)?=?1.37, 95% confidence interval (CI)?=?0.98–1.92]. High anti- T. gondii IgG antibody levels (&150 IU/mL) were found in 27 (47.4%) of the 57 anti- T. gondii IgG-positive patients and in 37 (28.7%) of the 129 anti- T. gondii IgG positive controls with a significant difference (OR?=?2.23, 95% CI?=?1.17–4.26). Anti- T. gondii IgM antibodies were found in 13 (22.8%) of the 57 seropositive patients and in 37 (28.7%) of the 129 seropositive controls, but the difference was not significant (OR?=?0.73, 95% CI?=?0.35–1.52). Seroprevalence was significantly higher in patients aged &50 years than in controls of the same age and in female patients than in female controls. Conclusions These findings indicate that a history of blood transfusion is a risk factor for T. gondii infection.
机译：目的进行这项研究是为了确定对弓形虫的血清阳性与输血史之间的关系。方法对接受过输血（n = 410），年龄和性别相匹配的未进行输血（n = 1230）的患者进行抗-T。ndii IgG和IgM抗体的酶检测。连锁免疫测定。结果在57名（13.9％）患者和129名（10.5％）对照中检出了抗弓形虫IgG抗体，其临界差值[比值比（OR）？=？1.37，95％置信区间（CI）？=？]。 0.98–1.92]。在57例抗弓形虫IgG阳性患者中的27例（47.4％）和129例抗T弓形虫中的37例（28.7％）中发现了高抗弓形虫IgG抗体水平（> 150 IU / mL） 。刚地IgG阳性对照具有显着差异（OR？=？2.23，95％CI？=？1.17–4.26）。在57名血清阳性患者中有13名（22.8％）和129名血清阳性对照中的37名（28.7％）发现了抗弓形虫IgM抗体，但差异无显着性（OR = 0.73，CI = 95％）。 =？0.35–1.52）。年龄大于50岁的患者的血清阳性率显着高于相同年龄的对照组和女性患者的血清阳性率。结论这些发现表明输血史是弓形虫感染的危险因素。

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