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首页> 外文期刊>Journal of Indian Society of Periodontology >Efficacy of herbal dentifrice on the prevention of plaque and gingivitis as compared to conventional dentifrice: A systematic review and meta-analysis
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Efficacy of herbal dentifrice on the prevention of plaque and gingivitis as compared to conventional dentifrice: A systematic review and meta-analysis

机译：与常规洁牙剂相比，中草药洁牙剂对预防牙菌斑和牙龈炎的功效：系统评价和荟萃分析

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Objective: The aim of this study was to review literature on the effects of herbal dentifrice compared to conventional dentifrice on plaque and gingival inflammation. Materials and Methods: MEDLINE, Cochrane Central Register of Controlled Trials, and major journals were explored for studies up to September 30, 2017. A comprehensive search was designed and the articles were independently screened for eligibility by two reviewers. Randomized controlled clinical trials, in which oral prophylaxis was undertaken before the intervention was introduced into the oral cavity using toothbrush were included. Where appropriate, a meta-analysis (MA) was performed and standardized mean differences (SMDs) were calculated. Results: Ten articles out of 1378 titles were found to meet the eligibility criteria. A MA showed that for plaque intervention the SMD was 2.14; 95% confidence interval (CI): 0.88–3.41, P = 0.0009; test for heterogeneity: P I2 = 96% in favor of conventional dentifrice; and for gingival inflammation, the SMD was 1.37; 95% CI: 0.49–2.26, P = 0.002; test for heterogeneity: P I2 = 94% which also was in favor of conventional dentifrice. Subgroup analysis for plaque intervention and gingival inflammation in case of long-term (more than 4 weeks and up to 6 months) and short-term effects (minimum of 4 weeks) of herbal dentifrice showed no difference when compared to conventional dentifrice. Conclusion: Currently, there is no high-quality evidence to support or abnegate the anti-plaque and anti-gingivitis effects of the herbal dentifrice.
机译：目的：本研究的目的是回顾与传统洁牙剂相比，牙粉对牙菌斑和牙龈炎症的影响的文献。材料和方法：探索MEDLINE，Cochrane对照试验中央注册簿和主要期刊进行研究，直至2017年9月30日。进行了全面搜索，并由两名审阅者独立筛选了文章的资格。随机对照临床试验包括在使用牙刷将干预措施引入口腔之前进行口腔预防。在适当的情况下，进行荟萃分析（MA），并计算标准化的均数差（SMD）。结果：在1378个标题中，有10条符合资格标准。 MA表示斑块干预的SMD为2.14; 95％置信区间（CI）：0.88–3.41，P = 0.0009;异质性测试：P I 2 = 96％，有利于传统洁牙剂;对于牙龈发炎，SMD为1.37; 95％CI：0.49–2.26，P = 0.002;异质性测试：P I 2 = 94％，这也有利于传统洁牙剂。与传统洁牙剂相比，长期（超过4周且最多6个月）和短期效果（至少4周）的牙菌斑干预和牙龈炎症的亚组分析显示没有差异。结论：目前，尚无高质量的证据支持或取消草药洁齿剂的抗牙菌斑和抗牙龈炎的作用。

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