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首页> 外文期刊>Journal of International Medical Research >Reality of obesity paradox: Results of percutaneous coronary intervention in Middle Eastern patients
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Reality of obesity paradox: Results of percutaneous coronary intervention in Middle Eastern patients

机译：肥胖悖论的现实：中东患者经皮冠状动脉介入治疗的结果

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Objective The aim of this study was to assess the baseline clinical characteristics, coronary angiographic features, and adverse cardiovascular events during hospitalization and at 1 year of follow-up in obese patients compared with overweight and normal/underweight patients. Methods A prospective, multicenter study of consecutive patients undergoing percutaneous coronary intervention was performed. Results Of 2425 enrolled patients, 699 (28.8%) were obese, 1178 (48.6%) were overweight, and 548 (22.6%) were normal/underweight. Obese patients were more likely to be female and to have a higher prevalence of diabetes, hypertension, hypercholesterolemia, or previous percutaneous coronary intervention. Acute coronary syndrome was the indication for percutaneous coronary intervention in 77.0% of obese, 76.4% of overweight, and 77.4% of normal/underweight patients. No significant differences in the prevalence of multi-vessel coronary artery disease or multi-vessel percutaneous coronary intervention were found among the three groups. Additionally, no significant differences were found in stent thrombosis, readmission bleeding rates, or cardiac mortality among the three groups during hospitalization, at 1 month, and at 1 year. Conclusion The major adverse cardiovascular event rate was the same among the three groups throughout the study period. Accordingly, body mass index is considered a weak risk factor for cardiovascular comorbidities in Arab Jordanian patients.
机译：目的本研究的目的是评估肥胖患者与超重和正常/体重不足患者相比，在住院期间和随访1年的基线临床特征，冠状动脉造影特征和不良心血管事件。方法对连续性经皮冠状动脉介入治疗的患者进行前瞻性，多中心研究。结果2425名入选患者中，肥胖699名（28.8％），超重1178名（48.6％），正常/体重不足548名（22.6％）。肥胖患者更有可能是女性，并且患糖尿病，高血压，高胆固醇血症或以前经皮冠状动脉介入治疗的患病率更高。急性冠状动脉综合征是77.0％的肥胖，76.4％的超重和77.4％的正常/体重不足患者的经皮冠状动脉介入治疗的指征。在三组中，多支冠状动脉疾病或多支经皮冠状动脉介入治疗的患病率无显着差异。此外，在住院期间，1个月和1年时，三组之间在支架内血栓形成，再入失血率或心脏死亡率方面均无显着差异。结论在整个研究期间，三组的主要不良心血管事件发生率相同。因此，在阿拉伯约旦患者中，体重指数被认为是心血管合并症的弱风险因素。

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