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Evolutionary view of the AIDS process

机译：艾滋病过程的进化观

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It is generally accepted that human immunodeficiency virus (HIV) is the etiological agent of acquired immune deficiency syndrome. According to this claim, HIV was transferred to humans from contact with monkeys around 35–50 years ago. However, this claim has not been sufficiently confirmed epidemiologically. The spread and incubation period of the plague epidemic has led to the theory that the Black Death was caused by hemorrhagic viruses. Having examined detailed historical data, we have concluded that the bacterium Yersenia pestis was an infectious agent in the epidemic, together with another agent which we suggest was HIV. Our considerations were mainly based on the existence of the CCR5 delta 32 mutation, which protects against HIV infection and has been present in the Caucasian population for over 2000 years. The combination of two infectious agents led to the devastation of the Black Death, the removal of HIV carriers, and an increase in the number of CCR5Δ32 mutations in the Caucasian population. In sub-Saharan Africa, this epidemic and subsequent sanitation process did not occur, which explains the much higher level of HIV genetic information in this part of the world.
机译：人们普遍认为人类免疫缺陷病毒（HIV）是获得性免疫缺陷综合症的病原体。根据这一说法，大约在35至50年前，HIV是通过与猴子接触而传播给人类的。但是，这种说法尚未在流行病学上得到充分证实。鼠疫的传播和潜伏期已导致黑死病是由出血性病毒引起的理论。在检查了详细的历史数据后，我们得出结论，鼠疫耶尔森氏菌是该流行病的传染病原体，我们认为是艾滋病毒。我们的考虑主要基于CCR5 delta 32突变的存在，该突变可防止HIV感染，并且在白种人中已经存在了2000多年。两种传染因子的结合导致了黑死病的严重破坏，HIV携带者的清除以及高加索人口中CCR5Δ32突变数量的增加。在撒哈拉以南非洲，这种流行病和随后的卫生过程并未发生，这解释了世界这一地区的艾滋病毒基因信息水平更高。

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