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首页> 外文期刊>Journal of International Medical Research >Peripheral Arterial Occlusive Disease as a Predictor of the Extent of Coronary Atherosclerosis in Patients with Coronary Artery Disease with and without Diabetes Mellitus
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Peripheral Arterial Occlusive Disease as a Predictor of the Extent of Coronary Atherosclerosis in Patients with Coronary Artery Disease with and without Diabetes Mellitus

机译:周围动脉闭塞性疾病可预测有无糖尿病的冠状动脉疾病患者冠状动脉粥样硬化程度

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We evaluated the sensitivity and specificity of a diagnosis of peripheral arterial occlusive disease (PAOD) as a predictor of the severity of coronary artery disease (CAD) in patients with and without diabetes. A total of 302 patients were assigned to groups according to the angiographic severity of their CAD and their diabetes status. Both PAOD and severe PAOD were diagnosed by measuring the ankle-brachial index (ABI) and toe-brachial index (TBI). A diagnosis of PAOD had a low sensitivity (34.3%) but a high specificity (87.0%) for detecting patients with severe CAD. Sensitivity was higher in patients with diabetes (52.4%) than without (19.5%), whereas specificity was higher in patients without diabetes (95.4%) than those with diabetes (69.8%). A diagnosis of severe PAOD had a higher specificity (96.0%), but a very low sensitivity (16.4%). We conclude that a diagnosis of PAOD among patients with CAD had a low sensitivity but a high specificity for detecting those with severe CAD, particularly in patients without diabetes.
机译:我们评估了诊断和不诊断糖尿病患者冠状动脉疾病(CAD)严重程度的外周动脉闭塞性疾病(PAOD)诊断的敏感性和特异性。根据他们的CAD血管造影严重程度和糖尿病状况,将总共302名患者分为两组。通过测量踝臂指数(ABI)和脚趾臂指数(TBI)可以诊断出PAOD和严重PAOD。 PAOD诊断对于检测重度CAD患者的敏感性低(34.3%)但特异性高(87.0%)。糖尿病患者(52.4%)的敏感性高于无糖尿病患者(19.5%),而无糖尿病患者(95.4%)的特异性高于糖尿病患者(69.8%)。严重PAOD的诊断具有较高的特异性(96.0%),但敏感性非常低(16.4%)。我们得出的结论是,在患有CAD的患者中诊断PAOD具有较低的敏感性,但对检测患有严重CAD的患者(尤其是没有糖尿病的患者)的特异性很高。

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