...
  • 主题
高级搜索  >
历史搜索 清空历史
首页> 外文期刊>Journal of International Medical Research >Neuro-Beh?et’s syndrome with a severe ocular lesion
【24h】

Neuro-Beh?et’s syndrome with a severe ocular lesion

机译：Neuro-Behcet综合征伴严重眼部病变

获取原文
           
页面导航
  • 摘要
  • 著录项
  • 相似文献
  • 相关主题

摘要

Beh?et’s syndrome (BS) is an idiopathic, chronic, relapsing, multisystem, vascular-inflammatory disease. Neuro-Beh?et’s syndrome (NBS) is a subtype of BS that mainly involves the central nervous system. Because of the heterogeneous involvement of NBS and the limited yearly numbers of new cases of NBS, estimating its course, prognosis, and treatment effect is difficult. Therefore, the efficacy of treatment for any form of NBS is unclear. We experienced a male patient with NBS and severe right uveitis. He received high-dose intravenous methylprednisolone (1000 mg/day) pulse therapy for 3 days. Intravenous injection of cyclophosphamide (400 mg, twice a day) and oral administration of prednisone (40 mg in the morning, 20 mg in the evening) were applied. Uveitis was treated with retrobulbar injection of triamcinolone acetonide (40 mg per week). The patient’s response was rapid with improved symptoms and signs. The therapeutic regimen of patients with BS has greatly advanced, leading to evidence-based guidelines. Methylprednisolone pulse therapy is important in treatment of BS. Novel therapeutic options are currently being examined to improve the prognosis of BS. These efforts will undoubtedly shed new light on this complex syndrome.
机译：贝氏综合症（BS）是一种特发性，慢性，复发性，多系统性血管炎性疾病。神经贝氏综合症（NBS）是BS的一种亚型，主要累及中枢神经系统。由于国家统计局的参与程度不一，每年新增国家统计局新病例的数量有限，因此难以估计其病程，预后和治疗效果。因此，对于任何形式的NBS的治疗效果尚不清楚。我们经历了一名患有NBS和严重右葡萄膜炎的男性患者。他接受了大剂量静脉注射甲基泼尼松龙（1000毫克/天）的脉冲治疗，持续了3天。静脉注射环磷酰胺（400 mg，每天两次）和口服泼尼松（早晨40 mg，晚上20 mg）。眼球炎通过球后注射曲安奈德（每周40 mg）治疗。患者的反应迅速，症状和体征得到改善。 BS患者的治疗方案已大大提高，从而导致了循证指南。甲基泼尼松龙脉冲疗法对BS的治疗很重要。目前正在研究新颖的治疗选择，以改善BS的预后。这些努力无疑将为这种复杂的综合症提供新的思路。

著录项

相似文献

  • 外文文献
  • 中文文献
  • 专利
获取原文

客服邮箱：kefu@zhangqiaokeyan.com

京公网安备：11010802029741号 ICP备案号：京ICP备15016152号-6 六维联合信息科技 (北京) 有限公司©版权所有

  • 客服微信

  • 服务号