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The independent risk factors of early diarrhoea in enteral nutrition for ICU patients

机译：ICU患者肠内营养早期腹泻的独立危险因素

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Objective To investigate the prevalence of and factors associated with diarrhoea in the early stage of enteral nutrition in critically ill patients in intensive care units (ICUs).Methods This prospective, multicentre, observational study enrolled consecutive patients who were newly admitted to ICUs and received enteral nutrition treatment. Events were observed continuously for 7 days or until patients were transferred out of the ICU after enteral nutrition. Demographic and clinical data, enteral nutrition data, diarrhoea-related data and outcomes were recorded. A multivariate logistic regression analysis was used to analyse the risk factors for diarrhoea.Results The study included 533 patients, of whom 164 (30.8%) developed diarrhoea. Diarrhoea was most commonly observed on the first to third days after starting enteral nutrition treatment. The median (interquartile range) duration of diarrhoea was 2 (1–3) days. The administration of gastrointestinal prokinetic agents, the increase in acute physiological and chronic health scores and the pyloric posterior feeding method were independent risk factors for diarrhoea.Conclusion The increased severity of illness, the administration of gastrointestinal prokinetic agents and the pyloric posterior feeding method were independent risk factors for diarrhoea in critically ill ICU patients undergoing enteral nutrition treatment.
机译：目的探讨重症监护病房（ICU）危重患者肠内营养早期腹泻的患病率及相关因素。方法这项前瞻性，多中心，观察性研究纳入了新入院并接受肠内治疗的连续患者。营养治疗。连续7天观察事件，直到患者接受肠内营养后转出ICU。记录人口统计学和临床​​数据，肠内营养数据，腹泻相关数据和结果。结果使用本研究纳入533例患者，其中164例（30.8％）发生腹泻。开始肠内营养治疗后的第一到第三天最常观察到腹泻。腹泻的中位（四分位间距）持续时间为2（1-3）天。胃肠道动力剂的使用，急性生理和慢性健康评分的增加以及幽门后路喂养方法是腹泻的独立危险因素。结论疾病的严重程度增加，胃肠道动力剂的给药和幽门后路喂养方法是独立的接受肠内营养治疗的重症ICU患者腹泻的危险因素。

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