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首页> 外文期刊>Journal of International Medical Research >Thyroid Abnormalities in Lithium-Treated Patients with Bipolar Affective Disorder
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Thyroid Abnormalities in Lithium-Treated Patients with Bipolar Affective Disorder

机译：接受锂离子治疗的双相情感障碍患者的甲状腺异常

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The thyroid functions of 42 subjects with bipolar affective disorder receiving regular lithium therapy were analysed and their thyroid glands were examined by ultrasonography. Following the receipt of lithium therapy (duration 4–156 months), three subjects displayed subclinical hypothyroidism (7.1%), three subclinical hyperthyroidism (7.1%) and one hyperthyroidism (2.4%). Moreover, goitre was detected in 16 (38.1%) subjects. An increase in the conversion of free thyroxine (T4) to free tri-iodothyrosine (T3), which is an indication of mild thyroid dysfunction, was identified in 20 (47.6%) subjects, and was mostly seen in male subjects under 40 years of age and in those having weight gain. In conclusion, some thyroid dysfunctions were observed in the patients treated with lithium.
机译：分析了接受常规锂疗法治疗的42例双相情感障碍患者的甲状腺功能，并通过超声检查检查了他们的甲状腺。接受锂治疗后（持续时间4至156个月），三名受试者表现出亚临床甲状腺功能减退（7.1％），三名亚临床甲状腺功能亢进（7.1％）和一名甲状腺功能亢进（2.4％）。此外，在16名（38.1％）受试者中检出了甲状腺肿。在20名（47.6％）的受试者中发现了游离甲状腺素（T4）向游离三碘甲硫氨酸（T3）的转化增加，这表明是轻度的甲状腺功能不全，并且主要发生在40岁以下的男性受试者中年龄和体重增加的人。总之，在用锂治疗的患者中观察到一些甲状腺功能障碍。

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