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首页> 外文期刊>Journal of International Medical Research >Effect of Gentamicin-absorbed Collagen in Wound Healing in Pilonidal Sinus Surgery: A Prospective Randomized Study
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Effect of Gentamicin-absorbed Collagen in Wound Healing in Pilonidal Sinus Surgery: A Prospective Randomized Study

机译：庆大霉素吸收的胶原蛋白在鼻窦手术伤口愈合中的作用：一项前瞻性随机研究

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摘要

Pilonidal sinus is a common disease that causes the loss of many working hours, but treatment is variable and problematic. The effect of gentamicin-absorbed collagen on healing, infection and recurrence, and length of hospital stay were examined after pilonidal sinus surgery. Patients undergoing surgical treatment for pilonidal sinus were randomly assigned into two groups each of 40 patients. Both groups were treated with excision and primary closure under local anaesthesia. Group 1 (control) received oral antibiotics for 7 days post-operatively. In group 2, prior to wound closure, gentamicin-absorbed collagen sponges were placed on the sacral fascia and these patients did not receive oral post-operative antibiotic therapy. Patients in group 2 had a significantly shorter mean wound healing time, significantly lower infection and recurrence rates, and a significantly shorter hospital stay than those in group 1. It is concluded that implantation of a gentamicin-containing collagen sponge on the wound area in pilonidal sinus decreased the rates of infection and recurrence, and shortened the hospital stay.
机译：鼻窦炎是一种常见的疾病，会导致许多工作时间的损失，但是治疗方法却是可变的且有问题。绒毛窦手术后检查了庆大霉素吸收的胶原蛋白对愈合，感染和复发以及住院时间的影响。接受绒毛窦手术治疗的患者被随机分为两组，每组40例。两组均在局部麻醉下行切除和一次闭合治疗。第一组（对照组）术后7天接受口服抗生素治疗。在第2组中，在伤口闭合之前，将庆大霉素吸收的胶原海绵放置在on筋膜上，这些患者未接受术后口服抗生素治疗。与第1组相比，第2组的患者平均伤口愈合时间明显缩短，感染和复发率明显降低，并且住院时间明显缩短。结论是，在含绒毛膜的伤口区域植入了含有庆大霉素的胶原海绵。鼻窦降低了感染和复发率，并缩短了住院时间。

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