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首页> 外文期刊>Journal of International Medical Research >Clinicopathological Variables Associated with Lymph Node Metastasis and Prognostic Factors in pT2 Gastric Cancer
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Clinicopathological Variables Associated with Lymph Node Metastasis and Prognostic Factors in pT2 Gastric Cancer

机译：pT2胃癌的淋巴结转移及预后因素相关的临床病理变量。

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This retrospective study investigated the clinicopathological variables associated with lymph node metastasis and prognosis in 325 patients with pT2 gastric cancer in order to set out a foundation for the surgical management of this condition. Univariate and multivariate analyses identified factors that were predictive of lymph node metastasis. Cox regression analysis evaluated the effect of prognostic factors on survival. Tumour location, maximum tumour diameter, lymphatic invasion and total retrieved lymph nodes (tLN) were revealed as independent factors for lymph node metastasis in pT2a gastric cancer, whereas histological type, lymphatic invasion and tLN were associated with lymph node metastasis in patients with pT2b gastric cancer. Maximum tumour diameter, lymphatic invasion and metastatic lymph node (mLN) ratio, but not tLN, were independent prognostic factors in pT2a cancer. Maximum tumour diameter and mLN ratio, but not tLN, were independent prognostic factors in pT2b cancer. Overall, it is concluded that maximum tumour diameter and mLN ratio are important prognostic factors in pT2 gastric cancer.
机译：这项回顾性研究调查了325例pT2胃癌患者中与淋巴结转移和预后相关的临床病理学变量，从而为该病的外科治疗奠定了基础。单因素和多因素分析确定了可预测淋巴结转移的因素。 Cox回归分析评估了预后因素对生存的影响。肿瘤位置，最大肿瘤直径，淋巴管浸润和总回收淋巴结（tLN）是pT2a胃癌淋巴结转移的独立因素，而pT2b胃癌的组织学类型，淋巴管浸润和tLN与淋巴结转移有关癌症。最大肿瘤直径，淋巴管浸润和转移淋巴结（mLN）比（而非tLN）是pT2a癌症的独立预后因素。最大肿瘤直径和mLN比值（而非tLN）是pT2b癌症的独立预后因素。总的来说，可以得出结论，最大肿瘤直径和mLN比是pT2胃癌的重要预后因素。

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