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Antimicrobial Effect of Cyperus rotundus on Multiple Drug Resistant Pseudomonas aeruginosa Strains

机译:香附子对多种耐药铜绿假单胞菌菌株的抗菌作用

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Background: Medicinal use of plants dates long back in the history of the human beings and has recently gained a great deal of importance in treating different diseases. Due to the importance of Pseudomonas aeroginosa strains as agents responsible for common secondary infections and their resistance to antibiotics and disinfectants, the present study aimed at investigating the antimicrobial effects of the plant Cyperus rotundus on multiple drug resistant (MDR) P. aeruginosa strains.?Methods: Ethanolic extracts of Cyperus rotundus tuber were prepared by maceration. The antimicrobial effect of these extracts on P. aeruginosa isolates (ie., sensitive to antibiotics and multiple drug resistant strains), isolated from clinical and soil samples, was determined by both disk diffusion and broth microdilution methods..?Results: It was revealed that ethanolic extract concentrations of Cyperus rotundus tuber higher than 0.1 mg/ml suppresses the growth of all antibiotic sensitive and resistant P. aeruginosa strains which were used in this study.?Conclusion: It is concluded that Cyperus rotundus possesses antimicrobial properties and thus can be used in treating multidrug resistant P. aeruginosa-induced wounds and infections.
机译:背景:药用植物的历史可以追溯到人类的历史上,最近在治疗各种疾病中已变得非常重要。由于铜绿假单胞菌菌株作为负责常见继发感染的试剂及其对抗生素和消毒剂的抗性的重要性,因此本研究旨在研究圆形莎草对多种抗药性(MDR)铜绿假单胞菌菌株的抗菌作用。方法:浸软法制备香附子的乙醇提取物。通过圆盘扩散法和肉汤微稀释法确定了这些提取物对从临床和土壤样品中分离出的铜绿假单胞菌分离物(即对抗生素和多种耐药菌株敏感)的抗菌作用。结果:表明香附子的乙醇提取物浓度高于0.1 mg / ml会抑制本研究中使用的所有对抗生素敏感和耐药的铜绿假单胞菌菌株的生长。结论:香附子具有抗菌特性,因此可以用于治疗多药耐药的铜绿假单胞菌引起的伤口和感染。

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