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Meningococcal Meningitis Control in Iran: Five Year Comparative Study 2000-2004

机译:伊朗脑膜炎球菌性脑膜炎的控制:2000-2004年的五年比较研究

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The aim of this study was to compare the incidence and death rate of meningococcal meningitis among military and non military population in Iran from 2000 to 2004. All patients with clinical sign and symptoms of meningitis and para clinical findings were entered to the study from 21st March 2000 to 21st March 2004. Meningococcal meningitis was diagnosed on the basis isolation of the Neisseria meningitidis in culture. CSF samples were provided at admission before commencing antibiotic therapy. Based on laboratory standard procedure all isolates were identified and final analysis revealed total number of approved meningococcal meningitides. In this comparative study meningococcal meningitides were 65 and 1370 cases in military and non-military patients, respectively. However, the total recorded cases of death were 7 in military group and 173 in non-military population. The incidence rate were 1.22 and 0.6 in 100000 in non-military and military population, respectively. The incidence of meningococcal meningitis among military personnel shows a sharp decline due to compulsory vaccination at least 2 weeks before arriving to military training camps; nonetheless, sporadic cases of the disease do occur perhaps as a result of complement deficiency in patients themselves or very late vaccination (around 2-3 days before arriving to military training camps). The findings of this study, consistent time of vaccination could be effective factor in order to prevent the infection.
机译:这项研究的目的是比较2000年至2004年伊朗军人和非军人中脑膜炎球菌性脑膜炎的发病率和死亡率。所有具有脑膜炎的临床体征和症状以及部分临床表现的患者均于3月21日开始接受研究从2000年至2004年3月21日。在分离培养的脑膜炎奈瑟氏球菌的基础上,诊断出脑膜炎球菌性脑膜炎。入院前提供CSF样品,然后开始抗生素治疗。根据实验室标准程序,鉴定了所有分离株,最终分析显示批准的脑膜炎球菌脑膜炎总数。在这项比较研究中,军人和非军人患者的脑膜炎球菌脑膜炎分别为65和1370例。但是,记录的死亡总数在军事集团中为7例,在非军事人口中为173例。在非军事和军事人口中,100,000人的发病率分别为1.22和0.6。军事人员中的脑膜炎球菌性脑膜炎的发病率由于在到达军事训练营之前至少两周进行了强制接种而急剧下降;然而,该病确实有零星发生的情况,可能是由于患者自身补体缺乏或疫苗接种很晚(到达军事训练营之前约2-3天)。这项研究的发现,一致的接种时间可能是预防感染的有效因素。

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