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首页> 外文期刊>Journal of Medical Case Reports >Primary adenocarcinoma in the ileostomy of a woman with familial adenomatous polyposis: a case report and literature review
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Primary adenocarcinoma in the ileostomy of a woman with familial adenomatous polyposis: a case report and literature review

机译：女性家族性腺瘤性息肉病回肠造口术中的原发性腺癌：一例病例报告并文献复习

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Introduction Ileal adenomas associated with familial adenomatous polyposis are a common finding. Many recent studies following panproctocolectomy for familial adenomatous polyposis have confirmed the presence of multiple ileal adenomas and an increase in ileal mucosal proliferation. In this study, we present a case of invasive adenocarcinoma arising in a severely dysplastic tubulovillous adenoma in the ileostomy of a patient with familial adenomatous polyposis; also, we present a literature review. To the best of our knowledge, only very few cases have been reported in the literature. Case presentation A 59-year-old Caucasian woman developed a primary adenocarcinoma in her ileostomy, complicating the stoma 31 years after its formation. Conclusions Primary adenocarcinoma following panproctocolectomy for familial adenomatous polyposis is a very rare clinical entity. The risk of developing adenocarcinoma in those patients increases with time. Patient education and medical examination of the stoma are of paramount importance and should be implemented early with the need of designing a surveillance protocol for early detection and management of ileal adenomas, especially in longstanding stomas.
机译：简介与家族性腺瘤性息肉病相关的回肠腺瘤是常见的发现。全结肠切除术治疗家族性腺瘤性息肉病后的许多最新研究已证实存在多个回肠腺瘤和回肠粘膜增生。在这项研究中，我们介绍了一例在家族性腺瘤性息肉病患者的回肠造口术中严重增生性微管结核性腺瘤中发生的浸润性腺癌;此外，我们提出了文献综述。据我们所知，文献中仅报道了很少的病例。病例介绍一名59岁的白种女人在回肠造口术中发展为原发性腺癌，使造口术形成31年后使其复杂化。结论全结肠切除术后原发性腺癌是家族性腺瘤性息肉病的罕见临床表现。这些患者患腺癌的风险随时间增加。对患者的造口教育和医学检查至关重要，应及早设计回盲腺瘤（特别是长期造口的回肠腺瘤）的监测方案。

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