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首页> 外文期刊>Journal of Medical Sciences >Changes of Hair Diameter after Treatment of Androgenic Alopecia; the First Case-control Study
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Changes of Hair Diameter after Treatment of Androgenic Alopecia; the First Case-control Study

机译：治疗雄激素性脱发后头发直径的变化;第一个病例对照研究

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Diminished hair diameter has been suggested as an early indicator of androgenic alopecia. The objective of the present work is to examine hair diameter changes after appropriate treatments in patients with androgenic alopecia, considering other possible interfering factors such as sex, natural hair color and location of hair sampling on the scalp. In a cross-sectional, case-control setting, 41 patients with androgenic alopecia (the case group) and 41 age and sex-matched healthy individuals (the control groups) were recruited from a referral dermatological center in Tabriz from September 2008 to December 2011. Patients received standard treatments for six months. Hair diameter was measured using a standard digital micrometer (Mitutoyo 0.001 mm, Japan) at baseline and six months later in both groups. In the case group, the mean hair diameter increased significantly from 0.052±0.008 to 0.055±0.008 m, 6 months later (p = 0.03). In the control group, the change of the mean hair diameter was not statistically significant in the controls. Frontal hairs were the While the mean hair diameter in female patients was higher, the mean change of hair diameter after treatment was significantly more in male patients. The mean hair diameter was significantly higher in light-brown than in dark-brown hairs of the patient?s thinnest samples, in this study. In conclusion, although hair diameter increased significantly after treatment, other factors such as gender, hair color and location on the scalp may also play significant roles in this regard.
机译：头发直径减少已被认为是雄激素性脱发的早期指标。本研究的目的是在考虑其他可能的干扰因素（例如性别，自然发色和头皮上的发丝位置）后，对雄激素性脱发患者进行适当治疗后检查发丝直径变化。在横断面病例对照研究中，从2008年9月至2011年12月从大不里士的转诊皮肤科中心招募了41例雄激素性脱发患者（病例组）和41例年龄和性别相匹配的健康个体（对照组）。患者接受了六个月的标准治疗。两组在基线时和六个月后使用标准数字千分尺（Mitutoyo 0.001 mm，日本）测量头发直径。在病例组中，6个月后，平均头发直径从0.052±0.008 m显着增加到0.055±0.008 m（p = 0.03）。在对照组中，平均毛发直径的变化在对照组中没有统计学意义。虽然女性患者的平均头发直径较高，但男性患者治疗后的平均头发直径变化明显更多。在这项研究中，患者最薄的样品的浅棕色头发的平均头发直径明显高于深棕色头发。总之，尽管治疗后头发直径显着增加，但其他因素（例如性别，头发颜色和头皮位置）在这方面也可能起重要作用。

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