• 主题
高级搜索  >
历史搜索 清空历史
首页> 外文期刊>Journal of Medical Sciences >Abnormal Serum Lipid Profile and Smoking are Associated with Plaque-type Psoriasi: A Case Control Study
【24h】

Abnormal Serum Lipid Profile and Smoking are Associated with Plaque-type Psoriasi: A Case Control Study

机译：斑块型牛皮癣与血脂异常和吸烟有关：病例对照研究

获取原文
           
页面导航
  • 摘要
  • 著录项
  • 相似文献
  • 相关主题

摘要

Psoriasis is a very commonly seen inflammatory condition in skin clinics. It has been suggested that this disease is associated with metabolic disease, particularly abnormalities in serum lipid profile . This study sought to examine possible association between plaque-type psoriasis and some individual variables of metabolic syndrome . After being approved by an ethical committee, 53 patients with plaque-type psoriasis were recruited along with 55 age and sex-matched healthy individuals as controls. The status of smoking, alcohol consumption and lipid profile including abnormally increases serum total cholesterol, Low Density Lipoprotein (LDL) and triglyceride, hypertension, diabetes mellitus and overweight/obesity were compared between the two groups. The case group was consisted of 27 males and 26 females with a mean age of 47.89±8.09 years. The controls were 35 males and 20 females with a mean age of 48.38±7.46 years. Smoking (43.4 vs. 20%, p = 0.01), increased serum total cholesterol (43.4 vs. 14.5%, p = 0.001), increased serum LDL (34 vs. 12.7%, p = 0.01) and hypertriglyceridemia (43.4 vs. 12.7%, p<0.001) were significantly higher in patients than in controls. These differences remained significant after logistic regression analysis. The two groups were comparable in terms of age (p = 0.74), sex (p = 0.18), alcohol consumption (p = 0.56), overweight/obesity (p = 0.74), hypertension (p = 0.33) and diabetes mellitus (p = 0.60). In conclusion, this study showed a significant association between smoking and abnormal lipid profile with psoriasis. Screening/preventive programs are recommended in this regard.
机译：牛皮癣是皮肤诊所中非常常见的炎症性疾病。已经表明该疾病与代谢疾病有关，特别是血清脂质分布异常。本研究旨在探讨斑块型牛皮癣与代谢综合征的一些个体变量之间的可能联系。经伦理委员会批准后，招募了53例斑块型牛皮癣患者以及55名年龄和性别相匹配的健康个体作为对照。比较两组的吸烟状况，饮酒状况和血脂状况，包括血清总胆固醇异常升高，低密度脂蛋白（LDL）和甘油三酸酯，高血压，糖尿病和超重/肥胖。病例组由27例男性和26例女性组成，平均年龄为47.89±8.09​​岁。对照组为35例男性和20例女性，平均年龄为48.38±7.46岁。吸烟（43.4 vs. 20％，p = 0.01），血清总胆固醇升高（43.4 vs. 14.5％，p = 0.001），血清LDL升高（34 vs. 12.7％，p = 0.01）和高甘油三酯血症（43.4 vs. 12.7） ％，p <0.001）在患者中显着高于对照组。经逻辑回归分析后，这些差异仍然很明显。两组在年龄（p = 0.74），性别（p = 0.18），饮酒（p = 0.56），超重/肥胖（p = 0.74），高血压（p = 0.33）和糖尿病（p = 0.60）。总之，这项研究表明吸烟与牛皮癣异常血脂水平之间存在显着相关性。在这方面，建议进行筛查/预防方案。

著录项

相似文献

  • 外文文献
  • 中文文献
  • 专利
获取原文

客服邮箱：kefu@zhangqiaokeyan.com

京公网安备：11010802029741号 ICP备案号：京ICP备15016152号-6 六维联合信息科技 (北京) 有限公司©版权所有

  • 客服微信

  • 服务号