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首页> 外文期刊>Journal of Medical Sciences >Impact of the Chloroform Extract of Carica papaya Seed on Oestrous Cycle and Fertility in Female Albino Rats
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Impact of the Chloroform Extract of Carica papaya Seed on Oestrous Cycle and Fertility in Female Albino Rats

机译：木瓜种子的氯仿提取物对雌性白化病大鼠发情周期和生育能力的影响

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摘要

The impact of oral administration of 100 mg kg 1 b.w of chloroform extract of Carica papaya seed (CPE) on oestrous cycle, fertility and serum 17 -oestradiol levels, in female rats was investigated. Ten proestrous rats received 2.5% tween 80 in normal saline (vehicle for CPE) and served as the control in each part of the study. In the oestrous cycle study, ten proestrous rats were treated with CPE for 14 days. The phases and frequencies of the oestrous cycles of the rats were determined daily for another 14 days while CPE treatment continued. In the fertility study, ten proestrous rats were treated as in the oestrous cycle study for 14 days and were thereafter cohabited with fertile untreated male rats for another 14 days while CPE treatment lasted. CPE did not adversely affect body weight of the rats. However there was a significant decrease (p Carica papaya seed has antifertility properties, possibly acting via inhibition of oestrogen secretion.
机译：研究了番木瓜种子（CPE）的氯仿提取物100 mg kg 1 b.w b.w对雌性大鼠雌性周期，生育力和血清17-雌二醇水平的影响。十只发情期大鼠在生理盐水（用于CPE的车辆）中接受2.5％的吐温80，并在研究的每个部分中作为对照。在发情周期研究中，用CPE治疗了10只发情期大鼠14天。在继续进行CPE治疗的同时，每天测定大鼠的发情周期的阶段和频率，持续14天。在生育力研究中，按照雌性周期研究，将十只发情期大鼠治疗14天，然后在CPE治疗持续的同时与未治疗的可育雄性大鼠同居14天。 CPE对大鼠的体重没有不利影响。但是，显着降低（p番木瓜种子具有抗生育性能，可能通过抑制雌激素分泌发挥作用。

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