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Skin Lesions Induced by Sodium Lauryl Sulfate (SLS) in Rabbits

机译:月桂基硫酸钠(SLS)引起的兔皮肤损伤

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The objective of this experimental study was to elucidate the damaging effect of sodium lauryl sulfate on the skin of rabbits. Ten adult domestic rabbits (5 males, 5 females) maintained at Animal house, were used. The animals were exposed to 5% solution of sodium lauryl sulfate, by brushing on the back region, for 8 weeks (between October and December 2004). All exposed rabbits developed wide area of allopacia (hair loss) and frequent skin erosions. The affected skin was dried and wrinkled. The animals were depressed and markedly emaciated. The clinical signs commenced with the onset of the skin lesions. It was concluded that sodium lauryl sulfate is a skin irritant and can provoke skin lesions in the form of eczyma and dermatitis.
机译:本实验研究的目的是阐明月桂基硫酸钠对兔子皮肤的伤害作用。使用动物舍饲养的十只成年家兔(5只雄性,5只雌性)。通过在背部刷牙,使动物暴露于5%月桂基硫酸钠溶液中8周(在2004年10月至2004年12月之间)。所有裸露的兔子都出现了大面积的白粉病(脱发)和频繁的皮肤糜烂。患处皮肤干燥并起皱。动物沮丧并且明显消瘦。临床症状始于皮肤病变的发作。结论是月桂基硫酸钠对皮肤有刺激性,可以引起皮损,皮炎和皮炎。

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