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Effects of Bermuda Grass (Cynodon dactylon) Extracts on Some Haematological Parameters of Streptozotocin-Induced Wistar Albino Rats

机译:百慕大草(Cynodon dactylon)提取物对链脲佐菌素诱导的Wistar白化病大鼠某些血液学参数的影响

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Effects of Aqueous and Ethanolic extracts of Cynodon dactylon on some haematological parameters (Fasting blood glucose, packed cell volume, heamoglobin, red blood cell, white blood cell and Fe 2+ /Fe 3+ ratio) of streptozotocin – induced diabetic wistar albino rats were investigated. Diabetes was induced by treatment with streptozotocin. Aqueous and ethanolic extracts of Cynodon dactylon at varying concentrations (300mg, 500mg and 700mg/kg body weight) were administered to the diabetic rats, and the findings revealed that aqueous and ethanolic extract of herbal preparation decreased the fasting blood glucose. The decrease was time and concentration dependent with 500mg/kg b/wt of aqueous and 300mg/kg b/wt of ethanolic extracts as the most effective. Also there was a significantly decrease (p0.05) effect on other parameters studied and as such could be beneficial in the management of diabetes.
机译:狗牙根的水和乙醇提取物对链脲佐菌素致糖尿病的维斯塔白化病大鼠的某些血液学参数(空腹血糖,堆积细胞体积,血红蛋白,红细胞,白细胞和Fe 2+ / Fe 3+比)的影响调查。通过用链脲佐菌素治疗诱导糖尿病。将不同浓度(300mg,500mg和700mg / kg体重)犬牙根的水提取物和乙醇提取物给予糖尿病大鼠,研究结果表明,草药提取物的水提取物和乙醇提取物降低了空腹血糖。减少取决于时间和浓度,其中最有效的是500mg / kg b / wt的水性提取物和300mg / kg b / wt的乙醇提取物。另外,对其他研究参数的影响也显着降低(p0.05),因此可能对糖尿病的治疗有益。

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