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Zika virus infection: a review of available techniques towards early detection

机译：寨卡病毒感染：早期检测可用技术的综述

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Zika virus belongs to the family Flaviviridae as do other viruses like Dengue, West Nile and Yellow Fever. They are arboviruses transmitted by the Aedes species of mosquito. Zika virus was first isolated in rhesus monkeys in Uganda in 1947. Human infections of the virus were found between the 1960s and 1980s in Africa, the Americas, Asia and the Pacific. The similarity in clinical presentation in Zika-infected patients compared with Dengue caused infections to be previously misdiagnosed as Dengue infection. The Zika virus pandemic in 2015 created a lot of concern globally because of little information about available techniques, samples as well as no available antiviral and vaccines for treatment and vaccination against infection. In addition, the vectors identified for transmission, Aedes aegypti and Aedes albopictus, were of great concern due to their ability to survive both temperate and tropical climatic conditions, hence indicating the possible global spread of Zika virus infection. Almost two years after the report of infection in pregnant women in Brazil resulting in microcephalic babies, Zika virus was identified as a public health problem. Thus, a lot of research into early detection and prevention has been conducted to control the spread of the virus. This review paper highlights available information on techniques currently available for diagnosis of infection caused by Zika virus.
机译：寨卡病毒属于黄病毒科，其他病毒如登革热，西尼罗河病毒和黄热病也属于黄病毒科。它们是由蚊的伊蚊属传播的虫媒病毒。寨卡病毒于1947年在乌干达的恒河猴中首次分离出来。在1960年代至1980年代之间的非洲，美洲，亚洲和太平洋地区发现了人感染这种病毒。与登革热相比，寨卡病毒感染患者的临床表现相似，导致先前被误诊为登革热感染。 2015年的寨卡病毒大流行在全球引起了广泛关注，因为关于可用技术，样品以及用于治疗和预防感染的可用抗病毒药和疫苗的信息很少。此外，由于其能够在温带和热带气候条件下生存，因此鉴定为可传播的载体埃及伊蚊和白纹伊蚊引起了极大的关注，因此表明寨卡病毒感染可能在全球传播。据报道，巴西孕妇感染导致小头畸形婴儿感染近两年后，寨卡病毒被确认为公共卫生问题。因此，已经进行了许多有关早期检测和预防的研究，以控制病毒的传播。这篇综述文章重点介绍了有关目前可用于诊断由寨卡病毒引起的感染的技术的可用信息。

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