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Study of Anaemia in Children with Severe Acute Malnutrition

机译:严重急性营养不良儿童贫血的研究

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Introduction : Severe anaemia is a leading cause of paediatric morbidity, hospitalization, and mortality and it is very important co morbidity in children with severe acute malnutrition. Severe Acute Malnutrition (SAM) with anaemia has been shown to have 2.62 times higher mortality as compared to SAM with no anaemia. So this study was done to evaluate this co-morbidity further. The aim of present study was to determine the prevalence and type of anaemia and to evaluate the possible aetiologies of anaemia in severe acute malnourished (SAM) children. Material and Methods : In tertiary care hospital a cross sectional study was conducted over a period of 8 month with 100 cases of SAM children and 101 cases of normal children. In both cases disorders of primary haematological problem were excluded. Auto analysers were used to measure blood counts. Blood smear was analysed by pathology consultant of institute and recorded for all patients with anaemia. Grade of anaemia and morphologic type of anaemia was analysed. Data were entered in Excel spreadsheets and analysed using SPSS 20.0. Results: Patient with SAM 42% had moderate anaemia and 19% had severe anaemia in contrast 41.6% and 16.8% in NON SAM child respectively. Predominant morphologic type in SAM patient was macrocytic anaemia (33%), while in controls microcytic anaemia (40.6%) was more prevalent. Conclusion: There was a high prevalence of anaemia in SAM children. Major morphologic type in SAM children was macrocytic anaemia which may indirectly show vitamin B12 or folic acid deficiency in these children. ?.
机译:简介:严重的贫血是小儿发病,住院和死亡的主要原因,它对于患有严重急性营养不良的儿童来说是非常重要的合并症。与没有贫血的SAM相比,患有贫血的严重急性营养不良(SAM)的死亡率高出2.62倍。因此,本研究旨在进一步评估这种合并症。本研究的目的是确定严重急性营养不良(SAM)儿童贫血的患病率和类型,并评估其可能的贫血病因。材料和方法:在三级医院进行了为期8个月的横断面研究,其中包括100例SAM儿童和101例正常儿童。在这两种情况下,均排除了原发性血液学问题的疾病。自动分析仪用于测量血细胞计数。该研究所的病理顾问对血液涂片进行了分析,并记录了所有贫血患者。分析贫血的程度和贫血的形态类型。将数据输入Excel电子表格并使用SPSS 20.0进行分析。结果:SAM患者中有42%患有中度贫血,19%患有严重贫血,而NON SAM儿童分别为41.6%和16.8%。 SAM患者的主要形态学类型是大细胞性贫血(33%),而对照组中的小细胞性贫血(40.6%)更为普遍。结论:SAM儿童贫血患病率很高。 SAM儿童的主要形态学类型是大细胞性贫血,可能间接表明这些儿童体内维生素B12或叶酸缺乏。 ?

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