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首页> 外文期刊>Journal of neurological sciences (Turkish) >A Comparison of Hyperdense Internal Carotid Artery Sign, Hyperdense Middle Cerebral Artery Sign and Middle Cerebral Artery Dot Sign in Acute Ischemic Stroke
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A Comparison of Hyperdense Internal Carotid Artery Sign, Hyperdense Middle Cerebral Artery Sign and Middle Cerebral Artery Dot Sign in Acute Ischemic Stroke

机译：急性缺血性卒中高密度内颈动脉征，高密度中脑动脉征和中脑动脉点征的比较

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Background: The aim of this study was to evaluate the clinical features of hyperdense internal carotid artery sign (HICAS), hyperdense middle cerebral artery sign (HMCAS) and MCA dot sign to understand their effect on the outcomes of acute ischemic stroke patients treated with intravenous recombinant tissue plasminogen activator (iv rtPA).Methods: Computed tomography (CT) scans, clinical features and outcomes of 252 patients with anterior circulation acute ischemic stroke treated with iv rtPA were evaluated. Initial CT scans were evaluated for hyperdense artery sign (HAS). Recanalization was evaluated with transcranial Doppler (TCD) in all available patients.Results: 99 of 252 patients had HAS; 12 had HICAS, 64 had HMCAS and 23 had MCA dot sign. None of the HICAS+ patients had a favorable outcome at three months. HMCAS+ patients achieved significantly less favorable outcomes. Mortality increased significantly in HICAS+ and HMCAS+ patients. MCA dot sign did not make a significant difference on baseline neurological status, recanalization, favorable outcome or mortality. At three months, there was no significant differences between HICAS and HMCAS whereas the MCA dot sign patients had better mRS scores compared with HICAS and HMCAS patients. HMCAS presence, baseline glucose levels and baseline NIHSS scores were all independent predictors of poor outcome.Conclusion: In acute ischemic stroke patients treated with iv rtPA, the presence of HICAS or HMCAS was found to be associated with insufficient recanalization and poor outcome, whereas MCA dot sign was a different entity and did not significantly influence the clinical course or outcome.
机译：背景：本研究旨在评估高密度颈内动脉征象（HICAS），高密度脑中动脉征象（HMCAS）和MCA点征的临床特征，以了解它们对静脉注射治疗的急性缺血性中风患者预后的影响方法：对252例接受iv rtPA治疗的前循环急性缺血性卒中患者的计算机断层扫描（CT）扫描，临床特征和结果进行评估。最初的CT扫描评估了高密度动脉征象（HAS）。结果：252例患者中有99例有HAS;经颅多普勒（TCD）评估了再通。其中12个具有HICAS，64个具有HMCAS，23个具有MCA点符号。 HICAS +患者在三个月内均未获得良好的预后。 HMCAS +患者的不良预后显着降低。 HICAS +和HMCAS +患者的死亡率显着增加。 MCA点征在基线神经系统状态，再通，良好的预后或死亡率方面无显着差异。在三个月时，HICAS和HMCAS之间没有显着差异，而MCA点征患者的mRS评分高于HICAS和HMCAS患者。 HMCAS的存在，基线血糖水平和基线NIHSS评分都是不良预后的独立预测因素。结论：在接受iv rtPA治疗的急性缺血性中风患者中，HICAS或HMCAS的存在与再通不足和预后不良有关，而MCA点号是一个不同的实体，并没有显着影响临床过程或结果。

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