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首页> 外文期刊>Journal of Nepal Paediatric Society >Correlation between Insulin Like Growth Factor -1 and Anthropometric Measurements of Premature Infants
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Correlation between Insulin Like Growth Factor -1 and Anthropometric Measurements of Premature Infants

机译:胰岛素样生长因子-1与早产儿人体测量的相关性

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Introduction: It is agreed that insulin like growth factor 1 (IGF- 1) influence growth. IGF-1) is a significant endocrine mediator of growth and encourages cellular propagation, survival, and differentiation. The aim of this study was to correlate insulin like growth factor 1 and anthropometric measurements in the neonatal age of the premature infants. Material and Methods: This study was performed at a level III intensive care unit at Suez Canal university hospital, Ismailia, Egypt. It is a cross sectional analytical study in the period from the March 2014 to September 2014. All cases are premature and were imperiled to history taking, clinical examination includes weight, length, head circumference and measurement of serum (IGF-1). Results: There were a total of 40 neonates. Gestational age extended from 31 to 36 weeks with a mean of 34.32±1.68 weeks; weight ranged from 1.15 to 3.20 kg with a mean of 2.14±0.59 kg and length ranged from 37 to 49 cm with a mean of 43.85±3.25 cm. Regarding neonatal gender, 21 neonates out of 40 neonates (52.5%) were males and 19 neonates (47.5%) were females. Mother’s age ranged from 19 to 35 years with a mean of 27.47±4.46 years. IGF- 1α concentration, it ranged from 13.55 ng/ml to 163.34 ng/ml with a mean of 99.64±32.43 ng/ml and there was statistically significant decrease in neonates with restricted growth when compared to non-restricted growth group (77.67±30.92 ng/ml vs 121.62±13.64 ng/ml respectively). Conclusion: There was significant correlation between IGF-1α and weight and head circumference of preterm neonates. J Nepal Paediatr Soc 2016;36(1):24-27
机译:简介:同意胰岛素样生长因子1(IGF-1)影响生长。 IGF-1)是生长的重要内分泌介质,可促进细胞增殖,存活和分化。这项研究的目的是将胰岛素样生长因子1和人体测量结果与早产儿的新生儿年龄联系起来。材料和方法:本研究在埃及伊斯梅利亚苏伊士运河大学医院的III级重症监护室进行。这是一项横断面分析研究,时间为2014年3月至2014年9月。所有病例均过早并有病史,临床检查包括体重,身长,头围和血清测量(IGF-1)。结果:共有40例新生儿。妊娠年龄从31周延长至36周,平均34.32±1.68周。重量范围为1.15至3.20千克,平均范围为2.14±0.59千克,长度范围为37至49厘米,平均范围为43.85±3.25厘米。在新生儿性别方面,40名新生儿中的21名新生儿(52.5%)是男性,而19名新生儿(47.5%)是女性。母亲的年龄介于19至35岁之间,平均年龄为27.47±4.46岁。 IGF-1α浓度范围为13.55 ng / ml至163.34 ng / ml,平均值为99.64±32.43 ng / ml,与非限制生长组相比,具有限制生长的新生儿统计学上显着降低(77.67±30.92 ng / ml,分别为121.62±13.64 ng / ml)。结论:IGF-1α与早产儿体重和头围之间存在显着相关性。尼泊尔儿科学杂志2016; 36(1):24-27

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