• 主题
高级搜索  >
历史搜索 清空历史
首页> 外文期刊>Journal of neurological sciences (Turkish) >Clinical and Electrodiagnostic findings of n-Hexane Neuropathy
【24h】

Clinical and Electrodiagnostic findings of n-Hexane Neuropathy

机译：正己烷神经病的临床和电诊断结果

获取原文
           
页面导航
  • 摘要
  • 著录项
  • 相似文献
  • 相关主题

摘要

n-Hexane is an isomer of hexane and was identified as a peripheral neurotoxin in 1964. The solvents containing n-Hexane are used as cleaning agents in the printing, textile, furniture and shoemaking industries. Certain kinds of special glues used in the roofing, leather and shoe industries also contain n-hexane. Inhalation is the main route of occupational exposure. Symptoms of a sensorimotor type of neuropathy develops after a few months to a year of repeated overexposure to n-hexane. The first symptoms are sensory and consist of tingling, numbness, burning, or prickling sensations in the feet or toes. Usually there are mixed electrophysiological findings which include both axonal degeneration and demyelination. The neuropathology of n-hexane neuropathy is distinctive with axonal swelling and neurofilament accumulation. The only treatment is removal from n-hexane exposure and the prognosis is generally favorable. Recovery may take months to years. In Turkey n-Hexane is mostly used in the shoemaking industries, and neurotoxicity has been reported. We report 8 patients who were working in the same shoe/sandal manufacturer for a mean duration of 27 months (3 months-8 years). and presented with a subacute neuropathy. The mean age was 18 (16-22). All subjects had a subacute presentatian between 15 days and 3 months. Motor deficits were the main clinical manifestation, but the EMG study revealed a sensorimotor neuropathy in all patients. Delayed worsening of symptoms and signs after cessation of n-hexane exposure was observed in all cases. A sural nerve biopsy was done in 3 patientsHow to cite this article:G. YüKSEL, G. KARLIKAYA, K. TUTKAVUL, B. YILDIRIM, C. ?RKEN, H. T?REL?: Clinical and Electrodiagnostic findings of n-Hexane Neuropathy. J Neurol Sci [Turk] 2007;24:219-225How to cite this URL & PDF:G. YüKSEL, G. KARLIKAYA, K. TUTKAVUL, B. YILDIRIM, C. ?RKEN, H. T?REL?: Clinical and Electrodiagnostic findings of n-Hexane Neuropathy. J Neurol Sci [Turk] 2007 [cited 2007 September 19];24:219-225. Available from: http://jns.dergisi.org/text.php3?id=174 PDF: http://jns.dergisi.org/pdf/pdf_JNS_174.pdfE-mail of the corresponding author: gulbunyuksel@yahoo.com
机译：正己烷是己烷的异构体，在1964年被鉴定为周围神经毒素。含有正己烷的溶剂在印刷，纺织，家具和制鞋工业中用作清洁剂。在屋面，皮革和制鞋工业中使用的某些特殊胶水也包含正己烷。吸入是职业接触的主要途径。反复过度暴露于正己烷几个月至一年后，出现感觉运动型神经病变的症状。最初的症状是感觉症状，包括脚或脚趾发麻，麻木，灼热或刺痛感。通常有混合的电生理发现，包括轴突变性和脱髓鞘。正己烷神经病变的神经病理学特点是轴突肿胀和神经丝积聚。唯一的治疗方法是从正己烷中除去，预后一般良好。恢复可能需要数月至数年。在土耳其，正己烷主要用于制鞋业，并且有神经毒性的报道。我们报告了8名在同一鞋/凉鞋制造商工作的患者，平均病程为27个月（3个月至8年）。并表现出亚急性神经病。平均年龄为18（16-22）。在15天至3个月之间，所有受试者的亚急性presentatian。运动功能障碍是主要的临床表现，但EMG研究显示所有患者均存在感觉运动神经病。在所有情况下，观察到停止正己烷接触后症状和体征的延迟恶化。 3例患者做了腓肠神经活检。 YüKSEL，G。KARLIKAYA，K。TUTKAVUL，B。YILDIRIM，C.RKEN，H。T？REL ?：正己烷神经病的临床和电诊断结果。 J Neurol Sci [Turk] 2007; 24：219-225如何引用此URL和PDF：G。 YüKSEL，G. KARLIKAYA，K. TUTKAVUL，B. YILDIRIM，C.RKEN，H.T？REL ?:正己烷神经病的临床和电诊断结果。 J Neurol Sci [Turk] 2007 [引用2007年9月19日]; 24：219-225。可从以下网址获得：http://jns.dergisi.org/text.php3?id=174 PDF：http://jns.dergisi.org/pdf/pdf_JNS_174.pdf相应作者的电子邮件：gulbunyuksel@yahoo.com

著录项

相似文献

  • 外文文献
  • 中文文献
  • 专利
获取原文

客服邮箱：kefu@zhangqiaokeyan.com

京公网安备：11010802029741号 ICP备案号：京ICP备15016152号-6 六维联合信息科技 (北京) 有限公司©版权所有

  • 客服微信

  • 服务号