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首页> 外文期刊>Journal of Ophthalmology >Multiple Electrophysiological Markers of Visual-Attentional Processing in a Novel Task Directed toward Clinical Use
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Multiple Electrophysiological Markers of Visual-Attentional Processing in a Novel Task Directed toward Clinical Use

机译：视觉注意加工中针对临床使用的新任务中的多个电生理标记。

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Individuals who have sustained a mild brain injury (e.g., mild traumatic brain injury or mild cerebrovascular stroke) are at risk to show persistent cognitive symptoms (attention and memory) after the acute postinjury phase. Although studies have shown that those patients perform normally on neuropsychological tests, cognitive symptoms remain present, and there is a need for more precise diagnostic tools. The aim of this study was to develop precise and sensitive markers for the diagnosis of post brain injury deficits in visual and attentional functions which could be easily translated in a clinical setting. Using electrophysiology, we have developed a task that allows the tracking of the processes involved in the deployment of visual spatial attention from early stages of visual treatment (N1, P1, N2, and P2) to higher levels of cognitive processing (no-go N2, P3a, P3b, N2pc, SPCN). This study presents a description of this protocol and its validation in 19 normal participants. Results indicated the statistically significant presence of all ERPs aimed to be elicited by this novel task. This task could allow clinicians to track the recovery of the mechanisms involved in the deployment of visual-attentional processing, contributing to better diagnosis and treatment management for persons who suffer a brain injury.
机译：遭受轻度脑损伤（例如轻度脑外伤或轻度脑​​血管中风）的个体在急性损伤后阶段有表现出持续性认知症状（注意力和记忆力）的风险。尽管研究表明这些患者在神经心理学测试中表现正常，但仍存在认知症状，因此需要更精确的诊断工具。这项研究的目的是开发用于诊断脑损伤后视觉和注意力功能缺陷的精确而敏感的标志物，这些标志物可以在临床环境中轻松翻译。利用电生理学，我们开发了一项任务，可以跟踪从视觉治疗的早期阶段（N1，P1，N2和P2）到更高水平的认知过程（不进行N2）的视觉空间注意力的部署过程，P3a，P3b，N2pc，SPCN）。这项研究介绍了该协议及其在19名正常参与者中的验证的描述。结果表明，旨在通过这项新任务引发的所有ERP都具有统计意义。该任务可以使临床医生跟踪视觉注意处理的部署所涉及的机制的恢复情况，从而有助于为脑损伤患者提供更好的诊断和治疗管理。

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