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首页> 外文期刊>Journal of Oral Microbiology >Bacterial Communities within Gingival Tissues from Periodontal Lesions Compared with Subgingival Plaque
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Bacterial Communities within Gingival Tissues from Periodontal Lesions Compared with Subgingival Plaque

机译：牙周病变牙龈组织中的细菌群落与牙龈下菌斑相比

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Periodontitis is caused by dysbiosis of subgingival plaque that results in increased bacterial invasion into gingival tissues. Although shifts in subgingival microbiota from healthy to periodontitis have been well characterized, the characteristics of bacterial communities located within gingival tissues have not been studied. To characterize microbiota within the tissues of periodontal lesions in comparison with plaque microbiota, gingival tissues and subgingival plaque were obtained from the same tooth of patients with periodontitis (n = 7). A pyrosequencing analysis of the 16S rRNA gene revealed that species richness and diversity were not significantly different between the two communities. However, inter-subject variation in intra-tissue communities was smaller than that in plaque communities. Intra-tissue communities were characterized by decreased Firmicutes and increased Fusobacteria, compared with the plaque communities. Particularly, Fusobacterium nucleatum and Porphyromonas gingivalis w...
机译：牙周炎是由牙龈下斑块的生物失调引起的，导致细菌侵入牙龈组织的增加。尽管已经很好地表征了龈下微生物群从健康到牙周炎的转变，但是尚未研究位于齿龈组织内的细菌群落的特征。为了与牙菌斑菌群相比，鉴定牙周病变组织中的菌群，从牙周炎患者的同一颗牙齿中获得了牙龈组织和牙龈下菌斑（n = 7）。对16S rRNA基因的焦磷酸测序分析表明，两个群落之间物种丰富度和多样性没有显着差异。但是，组织内群落的受试者间变异小于斑块群落。与噬菌斑群落相比，组织内群落的特征是硬毛减少和梭菌增加。尤其是，核杆菌和牙龈卟啉单胞菌与...

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