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首页> 外文期刊>Journal of Oral Microbiology >Multilocus sequence typing (MLST) of JP2 genotype isolates of Aggregatibacter actinomycetemcomitans collected from carriers of African and non-African origin
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Multilocus sequence typing (MLST) of JP2 genotype isolates of Aggregatibacter actinomycetemcomitans collected from carriers of African and non-African origin

机译：从非洲和非非洲血统的携带者收集的放线杆菌聚合酶JP2基因型分离株的多基因座序列分型（MLST）

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摘要

The bacterium Aggregatibacter actinomycetemcomitans is associated with aggressive periodontitis. Individuals colonised with the highly leukotoxic JP2 genotype of the bacterium, are at increased risk for developing periodontitis. The JP2 genotype is considered to emerge from North Africa and subsequently spread to individuals of African origin, living geographically widespread including in other parts of Africa and outside Africa. Reports of non-African carriers of the JP2 genotype are scares. However, in this study we characterize by multilocus sequence analysis JP2 genotype isolates collected from individuals of both African and non- African origin.Materials and Methods: The study collection comprised 43 JP2 genotype strains. Among those 23 were isolated at the Clinical laboratory of Dental School, Ume?, Sweden, from samples collected from patients living in Sweden, but of both non-Africa and African origin. Seven housekeeping genes were sequenced and the strains were distributed according to dif...
机译：集合放线杆菌属细菌与侵袭性牙周炎有关。细菌的高度白毒性JP2基因型定居的个体患牙周炎的风险增加。 JP2基因型被认为是从北非出现的，随后传播到非洲血统的个体，在地理上广泛分布，包括在非洲其他地区和非洲以外。 JP2基因型的非非洲携带者的报道令人恐惧。但是，在这项研究中，我们通过多位点序列分析表征了从非洲和非非洲血统的个体收集的JP2基因型分离株。材料与方法：研究集合包括43株JP2基因型菌株。在这23种中，是从瑞典Ume？牙科学校的临床实验室中分离的，这些样品是从居住在瑞典但非非洲和非洲血统的患者那里收集的。对七个管家基因进行了测序，并根据菌株的不同分配了菌株。

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