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The role of periodontal niches in influencing the tongue microbiota: relationship with periodontitis and oral malodour

机译:牙周ni在影响舌头菌群中的作用:与牙周炎和口腔恶臭的关系

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The tongue microbiota is a major contributor to oral malodour. Clinical studies indicate an association between oral malodour and chronic periodontitis. In this study, microbiota on the tongue of individuals with oral health, chronic periodontitis and gingivitis, was characterized in relation to the periodontal microbiota. Tongue scrapings, subgingival and interdental plaque were collected, under an ethics approved protocol and sequenced using the HOMINGS protocol. Sequences were analysed using the Minimum Entropy Decomposition pipeline. Volatile Sulfur Compound (VSC) concentrations were measured in the breath of participants using Oral Chroma?. Plaque index scores in health and percentage of deep periodontal pockets (6mm) in gingivitis and periodontitis were positively associated with increased tongue α-diversity as measured by Inverse Simpson and Shannon indices. Breath methanethiol was associated with both clinical indices of periodontitis and the ecological differences observed in subgingival...
机译:舌菌群是导致口腔异味的主要因素。临床研究表明,口腔恶臭与慢性牙周炎之间存在关联。在这项研究中,口腔健康,慢性牙周炎和牙龈炎患者的舌头上的菌群与牙周菌群有关。根据伦理学批准的方案收集刮舌,龈下和齿间斑,并使用HOMINGS方案进行测序。使用最小熵分解流水线分析序列。使用口服色度法在参与者的呼吸中测量挥发性硫化合物(VSC)的浓度。通过逆辛普森和香农指数测得,牙菌斑健康指数得分以及牙龈炎和牙周炎的深层牙周袋百分比(> 6mm)与舌头α多样性增加呈正相关。呼吸中的甲硫醇与牙周炎的临床指标以及在龈下观察到的生态差异有关。

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