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Comorbidity of periodontal disease: two sides of the same coin? An introduction for the clinician

机译:牙周疾病合并症:同一枚硬币的两面?临床医生介绍

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Increasing evidence has suggested an independent association between periodontitis and a range of comorbidities, for example cardiovascular disease, type 2 diabetes, rheumatoid arthritis, osteoporosis, Parkinson’s disease, Alzheimer’s disease, psoriasis, and respiratory infections. Shared inflammatory pathways are likely to contribute to this association, but distinct causal mechanisms remain to be defined. Some of these comorbid conditions may improve by periodontal treatment, and a bidirectional relationship may exist, where, for example, treatment of diabetes can improve periodontal status. The present article presents an overview of the evidence linking periodontitis with selected systemic diseases and calls for increased cooperation between dentists and medical doctors to provide optimal screening, treatment, and prevention of both periodontitis and its comorbidities.
机译:越来越多的证据表明,牙周炎与一系列合并症之间存在独立的关联,例如心血管疾病,2型糖尿病,类风湿性关节炎,骨质疏松症,帕金森氏病,阿尔茨海默氏病,牛皮癣和呼吸道感染。共有的炎症途径可能促成这种关联,但是尚有不同的病因机制尚待确定。这些合并症中的某些可以通过牙周治疗来改善,并且可能存在双向关系,例如,糖尿病的治疗可以改善牙周状态。本文介绍了牙周炎与某些全身性疾病相关的证据概述,并呼吁牙医和医生之间加强合作,以提供最佳的筛查,治疗和预防牙周炎及其合并症的机会。

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