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Effect of maltitol-containing chewing gum use on the composition of dental plaque microbiota in subjects with active dental caries

机译:含麦芽糖醇的口香糖对活动性龋齿患者牙菌斑微生物群组成的影响

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Background: Sugar alcohols such as xylitol are incorporated in a number of oral hygiene products for their anti-cariogenic properties while chewing gum is known to be beneficial to oral hygiene.Objective: The aim of this study was to determine the composition of the dental plaque microbiota in patients with active caries before and after using a chewing gum supplemented with maltitol.Design: Forty subjects with active caries were randomly allocated to chew maltitol gum or gum base for two weeks. A healthy control group used gum base for two weeks. Plaque samples were collected before and after treatment and the microbiota analysed by pyrosequencing of 16S rRNA genes.Results: A total of 773,547 sequences were obtained from 117 samples. There was no difference in structure of the bacterial communities between groups (AMOVA). There was a significant difference in community membership between groups, (AMOVA, p=0.009). There was a significant difference between the control group after treatment and the...
机译:背景:糖醇(如木糖醇)因其抗龋齿作用而被掺入许多口腔卫生产品中,而口香糖对口腔卫生有益。目的:本研究的目的是确定牙菌斑的组成使用补充麦芽糖醇的口香糖前后患有活动性龋齿的患者的微生物群。设计:将四十名患有活动性龋齿的受试者随机分配至咀嚼麦芽糖醇胶或口香糖胶基两周。一个健康的对照组使用了口香糖基质两周。处理前后收集菌斑样品,并对16S rRNA基因进行焦磷酸测序分析菌群。结果:从117份样品中获得了773,547个序列。各组之间的细菌群落结构没有差异(AMOVA)。群体之间的社区成员之间存在显着差异(AMOVA,p = 0.009)。治疗后的对照组和治疗后的对照组之间存在显着差异。

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