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首页> 外文期刊>Journal of Oral Microbiology >Extended-spectrum beta-lactamase-producing bacteria are not detected in supragingival plaque samples from human fecal carriers of ESBL-producing Enterobacteriaceae
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Extended-spectrum beta-lactamase-producing bacteria are not detected in supragingival plaque samples from human fecal carriers of ESBL-producing Enterobacteriaceae

机译：在产ESBL肠杆菌科动物粪便的人粪便携带者的龈上菌斑样品中未检测到产生广谱β-内酰胺酶的细菌

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BackgroundThe prevalence of infections caused by Cefotaximase-Munich (CTX-M)-type extended-spectrum beta-lactamase-producing Enterobacteriaceae (ESBL-E) has rapidly increased during the past 15 years. Enterobacteriaceae are commonly found in the gastrointestinal tract and long-term intestinal carriage is considered important for the spread of ESBL and as a source of clinical infections. Oral biofilm such as supragingival plaque is known to contain numerous antibiotic resistance determinants and may also represent a poorly investigated site for ESBL carriage and further spread.ObjectiveTo investigate possible carriage of ESBL-producing bacteria in supragingival plaque of known fecal carriers of these bacteria.DesignWe screened for the presence of aerobic and anaerobic ESBL-producing bacteria and bla CTX-M in supragingival plaque samples from healthy human adults with culture-verified fecal carriage of CTX-M-producing Escherichia coli. The presence or absence of Enterobacteriaceae and ESBL-producing bacteri...
机译：背景技术在过去的15年中，由头孢噻肟酶慕尼黑（CTX-M）型超广谱β-内酰胺酶生产肠杆菌科（ESBL-E）引起的感染率迅速上升。肠杆菌科通常在胃肠道中发现，长期肠道运输对ESBL的传播和作为临床感染的来源很重要。已知诸如龈上菌斑的口腔生物膜包含许多抗生素抗性决定簇，并且也可能代表了ESBL携带和进一步传播的未充分研究的部位。目的研究这些细菌的已知粪便携带者的龈上菌斑中可能携带ESBL的细菌。用培养验证的粪便运输产生CTX-M的大肠杆菌筛选健康人成年人龈上菌斑样品中有氧和厌氧的ESBL产生细菌和bla CTX-M的存在。肠杆菌科和产ESBL细菌的存在与否...

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