Nafarzadeh SH1 Molania T2 Motallebnejad M3 Mehdizadeh M4 Aghel S 2 ? 1- Assistant Professor, Department of Oral and maxillofacial Pathology, Babol Dental School, Babol, Iran ? 2- Post graduate student, residence of Oral Medicine, Department of Oral Medicine of Babol Dental School, Babol, Iran ? 3- Associate Professor, Department of Oral Medicine, Babol Dental school,Babol,Iran ? 4- Assistant Professor of Oral and maxillofacial surgery, Department of Oral and maxillofacial surgery of Babol Dental school, Babol, Iran ? Corresponding Author : Aghel S.: Department of Oral Medicine ? Tel: 09121942844 Email: aghelsara@gmail.com ? ?Background and Aim: ? Benign oral fibrous histiocytoma is a rare lesion in the head and neck region . This tumor usually presents as a single nodular , painless mass which grows slowly and varies in size from 2- 3 cm to over 10 cm. Most patients are under 50 years of age and a history of trauma , chronic infection and sun exposure are reported . ? Case Report : In this paper a case of benign fibrous histiocytoma in the tongue of a 44 - year-old man is reported . In microscopic view spindle cell Fascicules , along with infiltration of multinucleated giant cells was presented and for definitive diagnosis immunohistochemistry staining for SMA, , Desmin, MSA, CD68 and CD34 was conducted. ? Conclusion: Microscopic feature of oral fibrous histiocytoma may be similar to some soft tissue tumors. Therefore, IHC is necessary for definite diagnosis. ? Keywords : Benign fibrous Histiocytoma, tongue, intraoral tumor,Immunohistochemistry
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