...
  • 主题
高级搜索  >
历史搜索 清空历史
首页> 外文期刊>Journal of Public Health Research >Epidemiology of cardiovascular malformations among newborns in Monchegorsk (north-west Russia): a register-based study
【24h】

Epidemiology of cardiovascular malformations among newborns in Monchegorsk (north-west Russia): a register-based study

机译：蒙切哥尔斯克（俄罗斯西北部）新生儿心血管畸形的流行病学：基于登记的研究

获取原文
           
页面导航
  • 摘要
  • 著录项
  • 相似文献
  • 相关主题

摘要

Background. Cardiovascular malformations (CVM) are one of the most prevalent groups of birth defects. Knowledge about the prevalence, distribution and survival in Russia has been limited. The aim of our study was to assess the perinatal prevalence, structure and risk factors for CVM among newborns in Monchegorsk (Murmansk Oblast, Russia) and the mortality among the affected newborns in the period 1973-2008. Design and methods. A register-based study on data from the Kola and Murmansk County Birth Registers. The study included 28,511 births. Results. The registered perinatal prevalence was 3.0 per 1000 newborns, with septal defects as the most prevalent. CVM was twenty times more prevalent among stillborn than live born, and one-third of the live born with a CVM died during the first week of life. The perinatal mortality rate with CVM was 442 per 1000 newborns. This indicator decreased over time. The mothers of newborns with a CVM were ten times more likely to have stillbirth in their anamnesis. The adjusted odds ratio between maternal smoking during pregnancy and CVM was 4.09 [95% confidence interval: 1.75-9.53]. Conclusions. The diagnosed perinatal prevalence was relatively low. A previous stillbirth by the mother was highly associated with being born with a CVM. An adjusted elevated risk was also observed among smoking mothers. Perinatal survival increased over time, but varied to a large extent between the different types of CVM.
机译：背景。心血管畸形（CVM）是最常见的先天缺陷组之一。关于俄罗斯的流行，分布和生存的知识是有限的。我们研究的目的是评估1973-2008年间蒙切哥尔斯克（摩尔曼斯克州，俄罗斯）新生儿的围产期患病率，CVM的结构和危险因素，以及受影响新生儿的死亡率。设计和方法。基于登记册的可拉和摩尔曼斯克县出生登记册数据的研究。该研究包括28511例出生。结果。登记的围产期患病率为每1000名新生儿3.0例，其中以间隔缺损最为普遍。 CVM在死胎中的发生率是活胎的20倍，并且有CVM的活胎中有三分之一在出生后的第一周死亡。 CVM的围产期死亡率为每1000名新生儿442例。该指标随时间下降。患有CVM的新生儿的母亲进行死育的可能性高十倍。孕妇在孕期吸烟与CVM之间的校正比值比为4.09 [95％置信区间：1.75-9.53]。结论。经诊断的围产期患病率较低。母亲先前的死产与CVM的出生密切相关。在吸烟母亲中也观察到了调整后的高风险。围产期生存率随时间增加，但是在不同类型的CVM之间差异很大。

著录项

相似文献

  • 外文文献
  • 中文文献
  • 专利
获取原文

客服邮箱：kefu@zhangqiaokeyan.com

京公网安备：11010802029741号 ICP备案号：京ICP备15016152号-6 六维联合信息科技 (北京) 有限公司©版权所有

  • 客服微信

  • 服务号