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首页> 外文期刊>Journal of Ethnobiology and Ethnomedicine >Arginine, scurvy and Cartier's
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Arginine, scurvy and Cartier's

机译：精氨酸，坏血病和卡地亚

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Several conifers have been considered as candidates for "Annedda", which was the source for a miraculous cure for scurvy in Jacques Cartier's critically ill crew in 1536. Vitamin C was responsible for the cure of scurvy and was obtained as an Iroquois decoction from the bark and leaves from this "tree of life", now commonly referred to as arborvitae. Based on seasonal and diurnal amino acid analyses of candidate "trees of life", high levels of arginine, proline, and guanidino compounds were also probably present in decoctions prepared in the severe winter. The semi-essential arginine, proline and all the essential amino acids, would have provided additional nutritional benefits for the rapid recovery from scurvy by vitamin C when food supply was limited. The value of arginine, especially in the recovery of the critically ill sailors, is postulated as a source of nitric oxide, and the arginine-derived guanidino compounds as controlling factors for the activities of different nitric oxide synthases. This review provides further insights into the use of the candidate "trees of life" by indigenous peoples in eastern Canada. It raises hypotheses on the nutritional and synergistic roles of arginine, its metabolites, and other biofactors complementing the role of vitamin C especially in treating Cartier's critically ill sailors.
机译：几种针叶树被认为是“ Annedda”的候选物，这是1536年雅克·卡蒂埃（Jacques Cartier）重病船员奇迹般治愈坏血病的来源。维生素C负责治疗坏血病，是从树皮中以易洛魁汤剂获得的。并从这种“生命之树”（通常被称为侧柏）离开。根据候选“生命之树”的季节性和昼夜氨基酸分析，在严冬期间制成的煎剂中也可能存在高水平的精氨酸，脯氨酸和胍基化合物。当食物供应有限时，半必需的精氨酸，脯氨酸和所有必需氨基酸将为维生素C从坏血病的快速恢复提供额外的营养益处。精氨酸的价值，特别是在危重病水手的康复中，被认为是一氧化氮的来源，而精氨酸衍生的胍基化合物是不同一氧化氮合酶活性的控制因素。这篇评论为加拿大东部土著人民使用候选“生命之树”提供了进一步的见解。它提出了关于精氨酸，其代谢物和其他生物因子的营养和协同作用的假设，补充了维生素C的作用，特别是在治疗卡地亚重病​​水手方面。

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