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首页> 外文期刊>Journal of Sports Science and Medicine >Immune Response in Women during Exercise in the Heat: A Spotlight on Oral Contraception
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Immune Response in Women during Exercise in the Heat: A Spotlight on Oral Contraception

机译：妇女在高温运动中的免疫反应：口服避孕药的焦点

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This study compared the immune and stress response of oral contraceptive users (WomenOC; n = 9) to normally-menstruating women (WomenNM; n = 9) at rest and during exercise in temperate (TEMP; 22°C) and hot (HEAT; 35°C) conditions. Participants performed a 3-stage cycling trial in each condition at 90% (Stage 1; 30 min), 135% (Stage 2; 15 min), and 180% (Stage 3; 7.5 min) of lactate threshold 1. C-reactive protein (CRP) and immune cell counts were measured at rest, and serum cytokines (IL-1β, IL-1RA, IL-6, IL-8, IL-10, and TNF-α) and salivary cortisol were evaluated before and after exercise in both the TEMP and HEAT conditions. There were no differences in resting immune cell counts between groups, nor any differences in cortisol or any of the pro- or anti-inflammatory cytokines measured at rest or after completion of the exercise trials (p > 0.05). However, a trend for a higher resting CRP concentration was observed in WomenOC relative to WomenNM (1.102 ± 1.182 and 0.326 ± 0.228, respectively, p = 0.07). The results obtained in the current study indicate similar immunoendocrine function in WomenOC and WomenNM both at rest and after exercise in temperate and hot environments.
机译：这项研究比较了在温度和温度（TEMP; 22°C）和炎热（HEAT; 35°C）条件。参与者在每种条件下以乳酸阈值1的90％（第1阶段; 30分钟），135％（第2阶段; 15分钟）和180％（第3阶段; 7.5分钟）进行了3阶段自行车试验。静息状态下测量蛋白质（CRP）和免疫细胞计数，并评估前后唾液皮质醇的血清细胞因子（IL-1β，IL-1RA，IL-6，IL-8，IL-10和TNF-α）在TEMP和HEAT条件下进行锻炼。两组之间的静息免疫细胞计数无差异，在静息或运动试验结束后测得的皮质醇或任何促炎或抗炎细胞因子也无差异（p> 0.05）。但是，在WomenOC中观察到相对于WomenNM而言，静息CRP浓度更高的趋势（分别为1.102±1.182和0.326±0.228，p = 0.07）。在当前研究中获得的结果表明，在温和和炎热的环境中休息和运动后，在WomenOC和WomenNM中免疫内分泌功能相似。

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