...
  • 主题
高级搜索  >
历史搜索 清空历史
首页> 外文期刊>Journal of Surgical Case Reports >Use of amniotic membrane graft in the surgical management of cicatricial ectropion associated with cetuximab therapy
【24h】

Use of amniotic membrane graft in the surgical management of cicatricial ectropion associated with cetuximab therapy

机译：羊膜移植物在西妥昔单抗治疗的瘢痕性外翻的外科治疗中的应用

获取原文
           
页面导航
  • 摘要
  • 著录项
  • 相似文献
  • 相关主题

摘要

Cetuximab (Erbitux) is an antiepidermal growth factor receptor (EGFR) monoclonal antibody that has been shown to delay the progression of metastatic colorectal cancer. The cutaneous side effects of cetuximab resulting from its effects on normal epidermal cells are well established. Periocular side effects, including blepharitis, trichomegaly, dry eye and conjunctivitis, have also been reported. We present a case of cicatricial ectropion associated with cetuximab therapy successfully managed with surgical repair using amniotic membrane graft. A 60-year-old man presented with bilateral lower eyelid cicatricial ectropion developing 3 days after the addition of cetuximab therapy to his baseline chemotherapeutic regimen. This was successfully managed with surgical repair using an amniotic membrane graft. Surgical repair with the amniotic membrane graft is a viable treatment option for cicatricial ectropion associated with EGFR inhibitor therapy.
机译：西妥昔单抗（Erbitux）是一种抗表皮生长因子受体（EGFR）单克隆抗体，已被证明可延迟转移性结直肠癌的进展。由西妥昔单抗对正常表皮细胞的作用引起的皮肤副作用已得到充分证实。还已经报道了眼周副作用，包括睑缘炎，滴虫，干眼症和结膜炎。我们介绍了一例与西妥昔单抗治疗相关的瘢痕性外翻，成功通过羊膜移植手术修复。一名60岁男子在基线化疗方案中加用西妥昔单抗治疗3天后出现双侧下睑瘢痕性外翻。通过使用羊膜移植物进行手术修复，成功地解决了这一问题。羊膜移植手术修复是与EGFR抑制剂治疗相关的瘢痕性外翻的可行治疗选择。

著录项

相似文献

  • 外文文献
  • 中文文献
  • 专利
获取原文

客服邮箱：kefu@zhangqiaokeyan.com

京公网安备：11010802029741号 ICP备案号：京ICP备15016152号-6 六维联合信息科技 (北京) 有限公司©版权所有

  • 客服微信

  • 服务号