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Carcinoid tumor of the lung metastatic to a previously identified pituitary adenoma

机译:肺类癌转移至先前确定的垂体腺瘤

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The authors present the case of a 58-year-old gentleman presenting with atypical carcinoid tumor of primary lung origin metastasizing to a previously identified pituitary macroadenoma. The patient presented with symptoms of headache and visual disturbance. Imaging revealed enlargement of a known sellar mass as well as three separate enhancing lesions in the brain parenchyma. Resection was accomplished via a transnasal transshpenoidal approach without complication. Immunoreactivity was demonstrated to synaptophysin, chromogranin, CD56, epithelial membrane antigen, and thyroid transcription factor-1. The specimen was also marked by negative staining for pituitary hormones. This case demonstrates a rare occurrence of metastastic spread of tumor to a previously identified pituitary macroadenoma.
机译:作者介绍了一个58岁的绅士的病例,他患有原发性肺源性非典型类癌,转移至先前发现的垂体大腺瘤。该患者表现出头痛和视觉障碍的症状。影像学检查显示,已知的蝶鞍肿块以及脑实质中三个单独的增强病变。切除是通过经鼻跨鼻窦入路完成的,没有并发症。免疫反应证明对突触素,嗜铬粒蛋白,CD56,上皮膜抗原和甲状腺转录因子-1。该标本还具有垂体激素阴性染色的特征。该病例表明肿瘤转移扩散至先前确定的垂体大腺瘤的罕见情况。

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