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首页> 外文期刊>Journal of the International Society of Sports Nutrition >Null effect of ginsenoside Rb1 on improving glycemic status in men during a resistance training recovery
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Null effect of ginsenoside Rb1 on improving glycemic status in men during a resistance training recovery

机译：人参皂甙Rb1在抵抗力训练恢复过程中对改善男性血糖状况的无效作用

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Background Ginsenoside Rb1, a principle active ingredients of Panax ginseng, has been shown to lower blood glucose in animals and increase insulin secretion in cultured insulinoma cells. The aim of this study was to determine the effects of daily ginsenoside Rb1 supplementation on circulating glucose and insulin levels in men during a 5-day recovery period after an acute bout of resistance exercise. Methods Twelve gymnasts (20.5?±?0.3 years of age) participated in this double blind placebo-controlled crossover trial. They were challenged by a lower-limb resistance exercise at a weight load of 85 % one-repetition maximal (1-RM) for 10 repetitions, six sets of the movement. Rb1 (1 ng/kg) or Placebo was orally delivered to participants daily during a 5-day recovery period after challenge. Circulating insulin, glucose and heart rate variability (HRV) were measured under fasted condition in the morning at Days 1, Day 3, and Day 5 during recovery. Results No significant effect of Rb1 on circulating glucose and insulin levels were found among participants during the 5-day recovery period. A persistent elevation in sympathetic nervous activity, indicated by increased HRV-low frequency/high frequency (HRV-LF/HF) power, during the Rb1 trial was observed. Conclusions The result of the study suggests that the null effect of Rb1 supplementation on lowering glucose and insulin levels of participants may be associated with chronic sympathetic activation.
机译：背景人参皂苷Rb1是人参的主要活性成分，已被证明可以降低动物体内的血糖并增加培养的胰岛素瘤细胞中的胰岛素分泌。这项研究的目的是确定在抵抗运动急性发作后的5天恢复期内，每天补充人参皂甙Rb1对男性循环葡萄糖和胰岛素水平的影响。方法12名体操运动员（年龄20.5±0.3岁）参加了这项双盲安慰剂对照的交叉试验。他们受到下肢抵抗运动的挑战，该运动的负重最大为一次重复运动（六组）的最大重复次数（85％）的一次重复运动（1-RM）10次。在激发后的5天恢复期内，每天口服Rb1（1 ng / kg）或安慰剂给参与者。在恢复期间的第1天，第3天和第5天的早晨，在禁食的条件下测量循环中的胰岛素，葡萄糖和心率变异性（HRV）。结果在5天的恢复期内，Rb1对参与者的循环葡萄糖和胰岛素水平没有显着影响。在Rb1试验期间，观察到交感神经活动持续升高，表现为HRV低频/高频（HRV-LF / HF）功率增加。结论研究结果表明，补充Rb1对降低参与者葡萄糖和胰岛素水平的无效作用可能与慢性交感神经激活有关。

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