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首页> 外文期刊>Journal of Veterinary Advances >Preliminary Study on the Contractile Effects of the Aqueous Extract of Leptadenia Hastata Leaf (Pers Decne) on Rat Uterus
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Preliminary Study on the Contractile Effects of the Aqueous Extract of Leptadenia Hastata Leaf (Pers Decne) on Rat Uterus

机译：Leptadenia Hastata叶子（Pers Decne）的水提取物对大鼠子宫收缩作用的初步研究

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The effect of the aqueous leaf extract of Leptadenia hastata on the contractile activity of the female uterus in rats was studied. The aqueous leaf extract was extracted with distilled water using a Soxhlet extractor and this yielded 24.1% w/w of the extract. The phytochemical study of Leptadenia hastata leaf was also determined and this revealed the presence of alkaloids, tannins, anthraquinones, phlobatannins, saponins, cardiac glycosides, flavonoids, carbohydrates and terpenoids. The uterus of seven adult intacton-pregnant virgin female rats were isolated and the effect of the extract on rat uterus was studied and measured on a kymograph. Uterine contractile activity was demonstrated by different doses of the extract. The results also show that the extract increases the length of uterine segments. It was thus concluded that the aqueous leaf extract of Leptadenia hastata has uterotonic principles which could be responsible for the oxytocic effects on the uterus and could therefore be used as an ecbolic. The identification of this phytochemical constituent would certainly be the focus of future studies.
机译：研究了Leptadenia hastata的水叶提取物对大鼠雌性子宫收缩活动的影响。使用索格利特提取器用蒸馏水提取叶片的水提取物，其提取量为提取物的24.1％w / w。 Leptadenia hastata叶片的植物化学研究也已确定，这表明存在生物碱，丹宁酸，蒽醌，phbbatannins，皂苷，强心苷，类黄酮，碳水化合物和类萜。分离了七只成年完整/未怀孕的处女雌鼠的子宫，研究了提取物对大鼠子宫的作用，并在运动仪上对其进行了测量。通过不同剂量的提取物证明了子宫的收缩活性。结果还表明，提取物增加了子宫段的长度。因此得出的结论是，Leptadenia hastata的水叶提取物具有子宫收缩作用，可能对子宫产生催产作用，因此可以用作促排卵剂。这种植物化学成分的确定无疑将是未来研究的重点。

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